Simple Summary In recent years, checkpoint inhibitor treatment of tumors has caused a stir.
The response of patients with metastases showed outstanding success for some cancer …

Over the past few decades, tremendous advances in the prevention, diagnosis, and
treatment of cancer have taken place. However for head and neck cancers, including oral …

Strategies to increase intratumoral concentrations of an anticancer agent are desirable to
optimize its therapeutic potential when said agent is efficacious primarily within a tumor but …

Adoptive cell therapy using TCR-engineered T cells (TCR-T cells) represents a promising
strategy for treating relapsed and metastatic cancers. We previously established methods to …

Simple Summary Mesenchymal conversion occurring in malignant epithelial neoplasms is
undesirable in tumors since it promotes more aggressive tumor behavior. This phenomenon …

Cancer-associated fibroblasts (CAFs) are the most abundant stromal cell population in
breast tumors. A functionally diverse population of CAFs increases the dynamic complexity …

Simple Summary Head and neck squamous cell carcinoma (HNSCC) is an aggressive and
lethal disease. Despite diagnostic and therapeutic advances, the overall survival of patients …

Oral cancer has been a major problem all across the globe, majorly in the developing
countries. With a growing emphasis in the field of cancer research, the contribution of the …

Simple Summary According to WHO 2018 estimates, cancer is the second leading cause of
mortality worldwide after cardiovascular disease, accounting for one in six fatalities. Mortality …

Background: Oral squamous cell carcinoma (OSCC) is a common cancer with high morbidity
and mortality. Alterations of antitumor immune responses are involved in the development of …