Cancer nanotechnology: current status and perspectives

JA Kemp, YJ Kwon - Nano convergence, 2021 - Springer
Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

The applications of nanozymes in cancer therapy: based on regulating pyroptosis, ferroptosis and autophagy of tumor cells

Y Zhang, W Yu, M Chen, B Zhang, L Zhang, P Li - Nanoscale, 2023 - pubs.rsc.org
Nanozymes are nanomaterials with catalytic properties similar to those of natural enzymes,
and they have recently been collectively identified as a class of innovative artificial enzymes …

A MOF-based potent ferroptosis inducer for enhanced radiotherapy of triple negative breast cancer

L Zeng, S Ding, Y Cao, C Li, B Zhao, Z Ma, J Zhou… - ACS …, 2023 - ACS Publications
Radiotherapy (RT) is one of the important clinical treatments for local control of triple-
negative breast cancer (TNBC), but radioresistance still exists. Ferroptosis has been …

All‐in‐one biomimetic nanoplatform based on hollow polydopamine nanoparticles for synergistically enhanced radiotherapy of colon cancer

L Gong, Y Zhang, J Zhao, Y Zhang, K Tu, L Jiao, Q Xu… - Small, 2022 - Wiley Online Library
Even though radiotherapy is the most important therapeutic strategy for colon cancer
treatment, there is an enormous demand to improve radiosensitivity in solid tumor …

Advances in radiotherapy and immunity in hepatocellular carcinoma

Y Yang, L Xiong, M Li, P Jiang, J Wang, C Li - Journal of Translational …, 2023 - Springer
Primary liver cancer is one of the most common malignant tumours worldwide; it caused
approximately 830,000 deaths in 2020. Hepatocellular carcinoma (HCC) is the most …

A bright future: advanced nanotechnology-assisted microwave therapy

Y Du, J Zhou, F He, P Zang, H Gong, C Liu, P Yang - Nano Today, 2023 - Elsevier
Microwave has a promising therapeutic future due to its excellent minimally invasive, tissue
penetrating and organ specificity. Microwave-triggered therapeutic technology has received …

In situ-transition nanozyme triggered by tumor microenvironment boosts synergistic cancer radio-/chemotherapy through disrupting redox homeostasis

Z Yuan, X Liu, J Ling, G Huang, J Huang, X Zhu, L He… - Biomaterials, 2022 - Elsevier
Disrupting redox homeostasis in the tumor microenvironment (TME), like excessive H 2 O 2,
glutathione (GSH) and weak acidity, has been proved as an effective tumor therapeutic …

Monte Carlo Simulation‐Guided Design of a Thorium‐Based Metal–Organic Framework for Efficient Radiotherapy‐Radiodynamic Therapy

Z Xu, T Luo, J Mao, C McCleary… - Angewandte Chemie …, 2022 - Wiley Online Library
High‐Z metal‐based nanoscale metal–organic frameworks (nMOFs) with photosensitizing
ligands can enhance radiation damage to tumors via a unique radiotherapy‐radiodynamic …

Alleviating the hypoxic tumor microenvironment with MnO2-coated CeO2 nanoplatform for magnetic resonance imaging guided radiotherapy

F Pi, X Deng, Q Xue, L Zheng, H Liu, F Yang… - Journal of …, 2023 - Springer
Background Radiotherapy is a commonly used tool in clinical practice to treat solid tumors.
However, due to the unique microenvironment inside the tumor, such as high levels of GSH …

Molecular pathways associated with oxidative stress and their potential applications in radiotherapy

R Liu, Y Bian, L Liu, L Liu, X Liu… - … Journal of Molecular …, 2022 - spandidos-publications.com
Radiotherapy is an essential and effective treatment modality for cancer. Excessive levels of
reactive oxygen species (ROS) induced by ionizing radiation disrupt the redox homeostasis …