Cardiovascular disease remains the leading cause of death in patients with diabetes.
Cardiovascular disease in diabetes is multifactorial, and control of the cardiovascular risk …

The recommendations listed in the present guideline are, whenever possible, evidence
based. An initial extensive evidence review, which included literature derived from research …

The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella …

There is now overwhelming evidence to support lowering LDL-c (low-density lipoprotein
cholesterol) to reduce cardiovascular morbidity and mortality. Statins are a class of drugs …

Abstract Treatment with statins, inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A
reductase, has proven beneficial preventive effects on cardiovascular events. However …

Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

Background Hydroxymethyl glutaryl coenzyme A reductase inhibitors, commonly called
statins, are some of the most commonly prescribed medications worldwide. Evidence …

Obesity, insulin resistance, type 2 diabetes mellitus and cardiovascular disease form a
metabolic disease continuum that has seen a dramatic increase in prevalence in developed …

Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to
assess whether this increase in risk is a consequence of inhibition of 3-hydroxy-3 …

Methods A total of 8,749 non-diabetic participants, aged 45–73 years, were followed up for
5.9 years. New diabetes was diagnosed in 625 men by means of an OGTT, HbA 1c≥ …