Differences between human embryonic stem cell lines

C Allegrucci, LE Young - Human reproduction update, 2007 - academic.oup.com
The promise of human embryonic stem cell (hESC) lines for treating injuries and
degenerative diseases, for understanding early human development, for disease modelling …

Cell therapy and the safety of embryonic stem cell-derived grafts

H Hentze, R Graichen, A Colman - Trends in biotechnology, 2007 - cell.com
Recent developments in the identification, in vitro culture and differentiation of stem cells
point to the unprecedented potential of these cells, or their derivatives, to cure degenerative …

Immunological considerations for embryonic and induced pluripotent stem cell banking

CJ Taylor, EM Bolton… - … Transactions of the …, 2011 - royalsocietypublishing.org
Recent advances in stem cell technology have generated enthusiasm for their potential to
study and treat a diverse range of human disease. Pluripotent human stem cells for …

Developing safe therapies from human pluripotent stem cells

MK Carpenter, J Frey-Vasconcells, MS Rao - Nature biotechnology, 2009 - nature.com
Developing safe therapies from human pluripotent stem cells | Nature Biotechnology Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research

R Josephson, CJ Ording, Y Liu, S Shin… - Stem …, 2007 - academic.oup.com
As the number of human embryonic stem cell (hESC) lines increases, so does the need for
systematic evaluation of each line's characteristics and potential. Comparisons between …

Converting human pluripotent stem cells into β-cells: recent advances and future challenges

CN Mayhew, JM Wells - Current opinion in organ transplantation, 2010 - journals.lww.com
Advances over the last decade suggest that generating functional β-cells from human PSCs
is achievable. However, there are aspects of β-cell development that are not well …

Concise review: parthenote stem cells for regenerative medicine: genetic, epigenetic, and developmental features

B Daughtry, S Mitalipov - Stem cells translational medicine, 2014 - academic.oup.com
Embryonic stem cells (ESCs) have the potential to provide unlimited cells and tissues for
regenerative medicine. ESCs derived from fertilized embryos, however, will most likely be …

Haplotype-based banking of human pluripotent stem cells for transplantation: potential and limitations

A Zimmermann, O Preynat-Seauve… - Stem cells and …, 2012 - liebertpub.com
High expectations surround the area of stem cells therapeutics. However, the cells' source—
adult or embryonic—and the cells' origin—patient-derived autologous or healthy donor …

Regulatory issues for personalized pluripotent cells

ML Condic, M Rao - Stem Cells, 2008 - academic.oup.com
The development of personalized pluripotent stem cells for research and for possible
therapies holds out great hope for patients. However, such cells will face significant …

Immunogenicity and allogenicity: a challenge of stem cell therapy

D Charron, C Suberbielle-Boissel… - Journal of cardiovascular …, 2009 - Springer
As age progresses, the regenerative power of one's own pluripotent stem cells is often
inadequate to sustain normal tissue function. Consequently, the incidence of chronic and …