The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …

With the advent of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
pandemic, several vaccines have been developed to mitigate its spread and prevent …

Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infections in adults that can result in hospitalizations. Estimating RSV-associated …

Objective Salmonella infection is a common cause of bacterial foodborne diseases (FBDs)
globally. In this study, we aimed to explore the epidemiological and etiological …

Influenza infection imparts an age-related increase in mortality and morbidity. The most
effective countermeasure is vaccination; however, vaccines offer modest protection in older …

As SARS-CoV-2 continues to spread globally, questions have emerged regarding the
strength and durability of immune responses in specific populations. In this study, we …

Background The relationship between postvaccination symptoms and strength of antibody
responses is unclear. The goal of this study was to determine whether adverse effects …

Knowledge of the mechanisms underpinning the development of protective immunity
conferred by mRNA vaccines is fragmentary. Here, we investigated responses to …

SARS-CoV-2 infection and vaccination generates enormous host-response heterogeneity
and an age-dependent loss of immune-response quality. How the pre-exposure T cell …