miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

Biosensing based on field-effect transistors (FET): Recent progress and challenges

D Sadighbayan, M Hasanzadeh… - TrAC Trends in Analytical …, 2020 - Elsevier
The use of field-Effect-Transistor (FET) type biosensing arrangements has been highlighted
by researchers in the field of early biomarker detection and drug screening. Their non …

Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Biomarker-activatable probes based on smart AIEgens for fluorescence and optoacoustic imaging

J Ouyang, L Sun, F Zeng, S Wu - Coordination Chemistry Reviews, 2022 - Elsevier
Fluorophores with aggregation-induced emission (AIE) are characterized by many
advantageous features for biomedical applications, including excellent photostability and …

Recent advances in cardiovascular disease biosensors and monitoring technologies

L Tang, J Yang, Y Wang, R Deng - ACS sensors, 2023 - ACS Publications
Cardiovascular disease (CVD) causes significant mortality and remains the leading cause of
death globally. Thus, to reduce mortality, early diagnosis by measurement of cardiac …

Microneedle-based transdermal detection and sensing devices

J Wang, Z Lu, R Cai, H Zheng, J Yu, Y Zhang, Z Gu - Lab on a Chip, 2023 - pubs.rsc.org
Microneedles have been expected for the construction of next-generation biosensors
towards personalization, digitization, and intellectualization due to their metrics of minimal …

Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

The key contribution of platelet and vascular arachidonic acid metabolism to the pathophysiology of atherothrombosis

L Badimon, G Vilahur, B Rocca… - Cardiovascular …, 2021 - academic.oup.com
Arachidonic acid is one of the most abundant and ubiquitous ω-6 polyunsaturated fatty acid,
present in esterified form in the membrane phospholipids of all mammalian cells and …

Antioxidant and anti-apoptotic potency of allicin and lycopene against methotrexate-induced cardiac injury in rats

M Aboubakr, A Farag, A Elfadadny, M Alkafafy… - … Science and Pollution …, 2023 - Springer
This study aimed to explore whether allicin (ALC) and lycopene (LP) could offer protection
against the harmful effects of methotrexate (MTX), a type of chemotherapy drug known for its …

A review of risk prediction models in cardiovascular disease: conventional approach vs. artificial intelligent approach

ASM Faizal, TM Thevarajah, SM Khor… - Computer methods and …, 2021 - Elsevier
Cardiovascular disease (CVD) is the leading cause of death worldwide and is a global
health issue. Traditionally, statistical models are used commonly in the risk prediction and …