Novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for oral delivery of olmesartan medoxomil: design, formulation, pharmacokinetic and …

A Nasr, A Gardouh, M Ghorab - Pharmaceutics, 2016 - mdpi.com
The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …

Applications and biocompatibility of mesoporous silica nanocarriers in the field of medicine

C Zhang, H Xie, Z Zhang, B Wen, H Cao… - Frontiers in …, 2022 - frontiersin.org
Mesoporous silica nanocarrier (MSN) preparations have a wide range of medical
applications. Studying the biocompatibility of MSN is an important part of clinical …

Nanostructured lipid carriers: versatile oral delivery vehicle

N Poonia, R Kharb, V Lather, D Pandita - Future science OA, 2016 - Future Science
Oral delivery is the most accepted and economical route for drug administration and leads to
substantial reduction in dosing frequency. However, this route still remains a challenge for …

[HTML][HTML] Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

PB Shekhawat, VB Pokharkar - Acta pharmaceutica sinica B, 2017 - Elsevier
Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: Recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

[HTML][HTML] Solubility of buprenorphine hydrochloride in supercritical carbon dioxide: Study on experimental measuring and thermodynamic modeling

G Sodeifian, MA Nooshabadi, F Razmimanesh… - Arabian Journal of …, 2023 - Elsevier
Nowadays, supercritical fluids (SCFs) technologies present a processing option for
obtaining new products with noteworthy characteristics. Access to reliable solubility data of …

An insight into preparatory methods and characterization of orodispersible film—A review

A Salawi - Pharmaceuticals, 2022 - mdpi.com
Over the past few decades, researchers and companies have been trying to develop novel
drug delivery systems to ensure safety, efficacy, compliance, and patient acceptability …

Nanocarriers for the delivery of active ingredients and fractions extracted from natural products used in traditional Chinese medicine (TCM)

Y Liu, N Feng - Advances in Colloid and Interface Science, 2015 - Elsevier
Traditional Chinese medicine (TCM) has been practiced for thousands of years with a recent
increase in popularity. Despite promising biological activities of active ingredients and …

Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration

RM Sábio, AB Meneguin, AM dos Santos… - Microporous and …, 2021 - Elsevier
The exploitation of mesoporous silica nanoparticles (MSNs) as drug delivery systems has
grown exponentially due to their remarkable tunable properties, such as high surface area …

Capsaicin-loaded solid lipid nanoparticles: Design, biodistribution, in silico modeling and in vitro cytotoxicity evaluation

S Kunjiappan, M Sankaranarayanan, BK Kumar… - …, 2020 - iopscience.iop.org
Lower doses of capsaicin (8-methyl-N-vanillyl-6-nonenamide) have the potential to serve as
an anticancer drug, however, due to its pungency, irritant effect, poor water solubility and …