[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

Nanoformulation strategies for improving intestinal permeability of drugs: A more precise look at permeability assessment methods and pharmacokinetic properties …

D Babadi, S Dadashzadeh, M Osouli… - Journal of controlled …, 2020 - Elsevier
The therapeutic efficacy of orally administered drugs is often restricted by their inherent
limited oral bioavailability. Low water solubility, limited permeability through the intestinal …

Transport mechanisms of solid lipid nanoparticles across Caco-2 cell monolayers and their related cytotoxicology

GH Chai, Y Xu, SQ Chen, B Cheng, FQ Hu… - … applied materials & …, 2016 - ACS Publications
Solid lipid nanoparticles (SLNs) have been extensively investigated and demonstrated to be
a potential nanocarriers for improving oral bioavailability of many drugs. However, the …

[HTML][HTML] Nanocarriers used in drug delivery to enhance immune system in cancer therapy

GCNB Lôbo, KLR Paiva, ALG Silva, MM Simões… - Pharmaceutics, 2021 - mdpi.com
Cancer, a group of diseases responsible for the second largest cause of global death, is
considered one of the main public health problems today. Despite the advances, there are …

Polymeric nanomedicines for poorly soluble drugs in oral delivery systems: An update

X Ma, RO Williams III - Journal of pharmaceutical investigation, 2018 - Springer
The field of nanomedicine offers promising new drug delivery systems with enhanced
properties. The literature has reported on the development of various nanomedicines that …

Solid lipid nanoparticles as an efficient drug delivery system of olmesartan medoxomil for the treatment of hypertension

NT Pandya, P Jani, J Vanza, H Tandel - Colloids and surfaces B …, 2018 - Elsevier
The aim of the current investigation was to develop solid lipid nanoparticles of olmesartan
medoxomil using hot homogenization method to improve its oral bioavailability. Central …

Polymer-lipid hybrid systems: merging the benefits of polymeric and lipid-based nanocarriers to improve oral drug delivery

S Rao, CA Prestidge - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: A number of biobarriers limit efficient oral drug absorption; both polymer-based
and lipid-based nanocarriers have demonstrated properties and delivery mechanisms to …

[HTML][HTML] Nanotechnology-based celastrol formulations and their therapeutic applications

PR Wagh, P Desai, S Prabhu, J Wang - Frontiers in Pharmacology, 2021 - frontiersin.org
Celastrol (also called tripterine) is a quinone methide triterpene isolated from the root extract
of Tripterygium wilfordii (thunder god vine in traditional Chinese medicine). Over the past …

Nanocarriers for oral drug delivery

L Zhang, S Wang, M Zhang, J Sun - Journal of drug targeting, 2013 - Taylor & Francis
The oral route for delivery of pharmaceuticals is widely used and accepted. However, many
biological therapeutics that have poor solubility, poor permeability, and/or poor stability in …

Nanocarriers as treatment modalities for hypertension

T Alam, S Khan, B Gaba, MF Haider, S Baboota… - Drug delivery, 2017 - Taylor & Francis
Hypertension, a worldwide epidemic at present, is not a disease in itself rather it is an
important risk factor for serious cardiovascular disorders including myocardial infarction …