PEGylation of PLA nanoparticles to improve mucus-penetration and colloidal stability for oral delivery systems
HighlightsSurface properties of PLA nanoparticles can be tuned to be used in oral drug
delivery.To let the oral administration of PLA nanoparticles since by themselves it is …
delivery.To let the oral administration of PLA nanoparticles since by themselves it is …
Development of chitosan nanoparticles as drug delivery system for a prototype capsid inhibitor
Oral delivery of biopharmaceutics drug disposition classification system (BDDCS) Class II or
IV drugs with poor aqueous solubility and poor enzymatic and/or metabolic stability is very …
IV drugs with poor aqueous solubility and poor enzymatic and/or metabolic stability is very …
Engineered Nanomaterials for Immunomodulation: A Review
The immune system usually provides a defense against invading pathogenic
microorganisms and any other particulate contaminants. Nonetheless, it has been recently …
microorganisms and any other particulate contaminants. Nonetheless, it has been recently …
Computational nanomedicine: modeling of nanoparticle-mediated hyperthermal cancer therapy
Nanoparticle-mediated hyperthermia for cancer therapy is a growing area of cancer
nanomedicine because of the potential for localized and targeted destruction of cancer cells …
nanomedicine because of the potential for localized and targeted destruction of cancer cells …
Tamoxifen-loaded poly (L-lactide) nanoparticles: development, characterization and in vitro evaluation of cytotoxicity
C Altmeyer, TK Karam, NM Khalil… - Materials Science and …, 2016 - Elsevier
In this study, poly (L-lactide)(PLA) nanoparticles containing Tamoxifen (Tmx) were
developed using an emulsion/solvent evaporation method, observing the influence of …
developed using an emulsion/solvent evaporation method, observing the influence of …
Recent advances on anti-HIV vaginal delivery systems development
SG Antimisiaris, S Mourtas - Advanced drug delivery reviews, 2015 - Elsevier
A review of the recent outcomes regarding technologies to prevent vaginal transmission of
HIV, mainly by using antiretroviral (ARV) drugs formulated as microbicides. An introduction …
HIV, mainly by using antiretroviral (ARV) drugs formulated as microbicides. An introduction …
Protein-lipid composite nanoparticles for the oral delivery of vitamin B12: Impact of protein succinylation on nanoparticle physicochemical and biological properties
Protein-lipid composite nanoparticles featuring three-layer structure (protein layer, α-
tocopherol layer and phospholipid layer) and an inner aqueous compartment have been …
tocopherol layer and phospholipid layer) and an inner aqueous compartment have been …
Preparation of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles by a microchannel technology
F Guo, D Guo, W Zhang, Q Yan, Y Yang… - European Journal of …, 2017 - Elsevier
Biodegradable polymeric nanoparticles (NPs) have potential therapeutic applications;
however, preparing NPs of a specific diameter and uniform size distribution is a challenge …
however, preparing NPs of a specific diameter and uniform size distribution is a challenge …
Mucopenetrating nanoparticles for enhancement of oral bioavailability of furosemide: in vitro and in vivo evaluation/sub-acute toxicity study
SES Radwan, MS Sokar, DA Abdelmonsif… - International Journal of …, 2017 - Elsevier
The aim of this study was to formulate and evaluate chitosan (CS)/alginate (ALG)
nanoparticles (NPs) loaded with furosemide (FSM) in an attempt to enhance its release …
nanoparticles (NPs) loaded with furosemide (FSM) in an attempt to enhance its release …
Scientific and regulatory considerations for generic complex drug products containing nanomaterials
In the past few decades, the development of medicine at the nanoscale has been applied to
oral and parenteral dosage forms in a wide range of therapeutic areas to enhance drug …
oral and parenteral dosage forms in a wide range of therapeutic areas to enhance drug …