The past several decades have witnessed the explosion of nanomedicine for cancer
therapy, where notable research efforts have been made in synthesizing and delivering …

Chitosan-coated nanoparticles are a promising class of drug delivery vehicles that have
been studied as tools for improving the gastrointestinal delivery of therapeutics. Here we …

Background Tetrandrine is an active constituent that is extracted from the root tuber of the
Chinese herb Stephania tetrandra S. Moore. It has shown various pharmacological effects …

Pancreatic cancer (PC), currently the third leading cause of cancer-related deaths in the
USA, is projected to become the second leading cause, behind lung cancer, by 2020. The …

Nanotechnology has been applied to the oral drug delivery for enhancing bioavailability
after oral administration. Numerous forms of reported nanomedicines are classified as lipid …

Nanotechnology is an emerging and promising technique, giving pavement to a novel
therapeutic domain, ie, nanomedicine. The drug molecules in nanomedicine are the same …

Olaparib (OLA) is a poly ADP ribose polymerase (PARP) inhibitor approved for germline
BRCA-mutated (gBRCAm) advanced ovarian cancer and breast cancer. Low oral …

Objectives: Lovastatin is an antilipidemic drug that belongs to the class of statins that has
poor oral bioavailability due to its low solubility and variable dissolution rate. The main aim …

Background: P-glycoprotein (P-gp), a well known ATP dependent efflux membrane
transporter, has been attracting considerable interests of medical researchers due to its …

Background This work focuses on the development of atorvastatin utilizing zein, a natural,
safe, and biocompatible polymer, as a nanosized formulation in order to overcome the poor …