Development of Perphenazine‐Loaded Solid Lipid Nanoparticles: Statistical Optimization and Cytotoxicity Studies

PA Farsani, R Mahjub, M Mohammadi… - BioMed Research …, 2021 - Wiley Online Library
Objective. Perphenazine (PPZ), as a typical antipsychotic medical substance, has the same
effectiveness compared to atypical antipsychotic medications for the treatment of …

Oral delivery of solid lipid nanoparticles: Underlining the physicochemical characteristics and physiological condition affecting the lipolysis rate

M Mahmoudian, S Maleki Dizaj, S Salatin… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Lipid-based nano-drug delivery systems (LBNDDSs) have gained widespread
attention in oral drug delivery due to their tunable and versatile properties such as …

Herbal nanomedicine interactions to enhance pharmacokinetics, pharmacodynamics, and therapeutic index for better bioavailability and biocompatibility of herbal …

R Kumar, M Sharma - Journal of Materials NanoScience, 2018 - pubs.thesciencein.org
Nanomedicine of herbs: Peoperties and Issues in application development The recent
developments in nanotechnology have unlocked new avenues in current research and play …

Controlling the size and morphology of griseofulvin nanoparticles using polymeric stabilizers by evaporation-assisted solvent–antisolvent interaction method

R Kumar, PF Siril - Journal of Nanoparticle Research, 2015 - Springer
Griseofulvin (GF) is a potential drug for cancer therapy. However, its application is limited by
its poor water solubility. Ultrafine GF nanoparticles were prepared through evaporation …

Polyionic hybrid nano-engineered systems comprising alginate and chitosan for antihypertensive therapeutics

T Niaz, H Nasir, S Shabbir, A Rehman… - International journal of …, 2016 - Elsevier
Hydrophobic nature of virtually all antihypertensive (AHT) drugs is the major hindrance
towards their oral administration. Current study focuses on the development of polyionic …

Nanosuspension: principles, perspectives and practices

S Kumar Singh, Y Vaidya, M Gulati… - Current drug …, 2016 - ingentaconnect.com
In the last three decades, nano-sizing of hydrophobic drugs has emerged as one of the most
commonly used strategies to overcome their solubility and bioavailability related issues …

Improved solubility and dissolution rate of ketoprofen by the formation of multicomponent crystals with tromethamine

L Fitriani, WA Firdaus, W Sidadang, H Rosaini… - Crystals, 2022 - mdpi.com
This study aims to improve the dissolution rate of ketoprofen by preparing multicomponent
crystals with tromethamine. The multicomponent crystals (equimolar ratio) of ketoprofen and …

Self-assembled casein nanoparticles loading triptolide for the enhancement of oral bioavailability

C Liu, T Jiang, Z Yuan, YU Lu - Natural Product …, 2020 - journals.sagepub.com
Triptolide (TP), a broad-spectrum antitumor drug, has very poor solubility and oral
bioavailability, which limits its clinical use. Compared with conventional formulations of TP, a …

Stability facilitation of nanoparticles prepared by ultrasound assisted solvent-antisolvent method: Effect of neem gum, acrylamide grafted neem gum and …

R Malviya, PK Sharma, SK Dubey - Materials Science and Engineering: C, 2018 - Elsevier
In present research, etoricoxib nanoparticles were prepared using newly developed
ultrasonication assisted solvent-antisolvent method. Neem gum (NGP) and their …

Olanzapine loaded nanostructured lipid carriers via high shear homogenization and ultrasonication

AL Ajiboye, U Nandi, M Galli, V Trivedi - Scientia Pharmaceutica, 2021 - mdpi.com
The aim of this study was to understand the effect of high shear homogenization (HSH) and
ultrasonication (US) on the physicochemical properties of blank and olanzapine loaded …