Transdermal administration of analgesic medications offers several benefits over alternative
routes of administration, including a decreased systemic drug load with fewer side effects …

Oxidative stress is associated with a wide range of diseases characterised by oxidant-
mediated disturbances of various signalling pathways and cellular damage. The only …

Nano-and Microscale Drug Delivery Systems: Design and Fabrication presents the
developments that have taken place in recent years in the field of micro-and nanoscale drug …

Pancreatic cancer is the fourth leading cause of death in the United States and has a 5-year
life expectancy of~ 8%. Currently, only a few drugs have been approved by the United …

More than 35 million people are living with HIV worldwide with approximately 2.3 million
new infections per year. Cascade of events (cell entry, virus replication, assembly and …

The endogenous molecule, S-adenosyl-l-methionine (SAMe) is a key factor due to its role in
the methylation cycle and modulation of monoaminergic neurotransmission. Since many …

The methacrylate copolymer Eudragit EPO (EPO) has previously shown to greatly enhance
solubilization of acidic drugs via ionic interactions and by multiple hydrophobic contacts with …

Background: The oral application of drugs is the most popular route through which the
systemic effect can be achieved. Nevertheless, oral administration is limited by difficulties …

Oral delivery of poorly bioavailable therapeuticals is challenging. The challenges are more
serious when physiological factors of gut such as cytochrome P450, P-glycoprotein …

The oral delivery of drugs with poor aqueous solubility is challenging and often results in
poor bioavailability. Various nanoformulation platforms have demonstrated improved oral …