Most adult organs contain regenerative stem cells, often organized in specific niches. Stem
cell function is critical for tissue homeostasis and repair upon injury, and it is dependent on …

Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

Immature dentate granule cells (imGCs) arising from adult hippocampal neurogenesis
contribute to plasticity and unique brain functions in rodents, and are dysregulated in …

The extent to which neurogenesis occurs in adult primates remains controversial. In this
study, using an optimized single-cell RNA sequencing pipeline, we profiled 207,785 cells …

Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …

Patients with Alzheimer's disease (AD) exhibit progressive memory loss, depression, and
anxiety, accompanied by impaired adult hippocampal neurogenesis (AHN). Whether AHN …

Alzheimer's disease (AD) is a chronic neurodegenerative disease, with the characteristics of
neurofibrillary tangle (NFT) and senile plaque (SP) formation. Although great progresses …

Physical exercise is of great significance for maintaining human health. Exercise can
provide varying degrees of benefits to cognitive function at all stages of life cycle. Currently …

Aging results in a decline in neural stem cells (NSCs), neurogenesis, and cognitive function,
and evidence is emerging to demonstrate disrupted adult neurogenesis in the hippocampus …

Alzheimer's disease (AD) is the most common form of age‐related dementia, characterized
by progressive memory loss and cognitive disturbances. The hippocampus, where adult …