Circulating cell-free DNA for cancer early detection

Q Gao, Q Zeng, Z Wang, C Li, Y Xu, P Cui, X Zhu, H Lu… - The Innovation, 2022 - cell.com
Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …

Circulating tumour cells for early detection of clinically relevant cancer

R Lawrence, M Watters, CR Davies, K Pantel… - Nature Reviews Clinical …, 2023 - nature.com
Given that cancer mortality is usually a result of late diagnosis, efforts in the field of early
detection are paramount to reducing cancer-related deaths and improving patient outcomes …

[HTML][HTML] The emerging role of cell-free DNA as a molecular marker for cancer management

AJ Bronkhorst, V Ungerer, S Holdenrieder - Biomolecular detection and …, 2019 - Elsevier
An increasing number of studies demonstrate the potential use of cell-free DNA (cfDNA) as a
surrogate marker for multiple indications in cancer, including diagnosis, prognosis, and …

Detection of circulating tumor cells and their implications as a biomarker for diagnosis, prognostication, and therapeutic monitoring in hepatocellular carcinoma

JC Ahn, PC Teng, PJ Chen, E Posadas, HR Tseng… - …, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is among the leading causes of worldwide cancer‐related
morbidity and mortality. Poor prognosis of HCC is attributed primarily to tumor presentation …

Tracking cancer progression: From circulating tumor cells to metastasis

F Castro-Giner, N Aceto - Genome medicine, 2020 - Springer
The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

ctDNA as a cancer biomarker: A broad overview

LS Pessoa, M Heringer, VP Ferrer - Critical reviews in oncology …, 2020 - Elsevier
Circulating tumor DNA (ctDNA) in fluids has gained attention because ctDNA seems to
identify tumor-specific abnormalities, which could be used for diagnosis, follow-up of …

Circulating tumor DNA as an early cancer detection tool

A Campos-Carrillo, JN Weitzel, P Sahoo… - Pharmacology & …, 2020 - Elsevier
Circulating tumor DNA holds substantial promise as an early detection biomarker,
particularly for cancers that do not have currently accepted screening methodologies, such …

[HTML][HTML] Liquid biopsy in ovarian cancer using circulating tumor DNA and cells: Ready for prime time?

DB Asante, L Calapre, M Ziman, TM Meniawy, ES Gray - Cancer letters, 2020 - Elsevier
Liquid biopsies hold the potential to inform cancer patient prognosis and to guide treatment
decisions at the time when direct tumor biopsy may be impractical due to its invasive nature …

Triple negative breast cancer: a review of present and future diagnostic modalities

SA Dass, KL Tan, R Selva Rajan, NF Mokhtar… - Medicina, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive breast type of cancer with no
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

Global mapping of cancers: The Cancer Genome Atlas and beyond

C Ganini, I Amelio, R Bertolo, P Bove… - Molecular …, 2021 - Wiley Online Library
Cancer genomes have been explored from the early 2000s through massive exome
sequencing efforts, leading to the publication of The Cancer Genome Atlas in 2013 …