Development of magnetic nanoparticles for cancer gene therapy: a comprehensive review

V Mulens, MP Morales… - International Scholarly …, 2013 - Wiley Online Library
Since they were first proposed as nonviral transfection agents for their gene‐carrying
capacity, magnetic nanoparticles have been studied thoroughly, both in vitro and in vivo …

Selective inhibition of proprotein convertases represses the metastatic potential of human colorectal tumor cells

N Scamuffa, G Siegfried, Y Bontemps… - The Journal of …, 2008 - Am Soc Clin Investig
The proprotein convertases (PCs) are implicated in the activation of various precursor
proteins that play an important role in tumor cell metastasis. Here, we report their …

[HTML][HTML] Insulin-like growth factor-1 receptor-targeted therapy for non-small cell lung cancer: a mini review

M Yin, X Guan, Z Liao, Q Wei - American journal of translational …, 2009 - ncbi.nlm.nih.gov
Lung cancer leads all other cancers in both incidence and mortality. Recent advances in
underlying molecular pathogenesis have validated a panel of protein tyrosine kinases as …

Increased expression of insulin‐like growth factor‐1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma

YH Wang, XD Han, Y Qiu, J Xiong, Y Yu… - Journal of Surgical …, 2012 - Wiley Online Library
Background The aim of this study was to investigate the association of insulin‐like growth
factor‐1 receptor (IGF‐1R) with metastasis and prognosis of osteosarcoma patients …

Caloric restriction coupled with radiation decreases metastatic burden in triple negative breast cancer

BA Simone, T Dan, A Palagani, L Jin, SY Han… - Cell Cycle, 2016 - Taylor & Francis
Purpose: Metastatic breast cancer is devastating and triple negative breast cancers (TNBC)
have a higher propensity for metastasis. Improved local control upfront in this aggressive …

[HTML][HTML] Anti-mucin1 aptamer-conjugated chitosan nanoparticles for targeted co-delivery of docetaxel and IGF-1R siRNA to SKBR3 metastatic breast cancer cells

R Jafari, NM Zolbanin, J Majidi, F Atyabi… - Iranian Biomedical …, 2019 - ncbi.nlm.nih.gov
Background: Targeted co-delivery of siRNA and a chemotherapeutic drug is an attractive
approach to cancer drug design and treatment. This study was carried out to design an anti …

MicroRNA-379 acts as a tumor suppressor in non-small cell lung cancer by targeting the IGF‑1R-mediated AKT and ERK pathways Retraction in/10.3892/or …

F Zhou, L Nie, D Feng, S Guo… - Oncology reports, 2017 - spandidos-publications.com
Lung cancer is one of the most common types of malignancy in humans and is a leading
cause of cancer-related deaths among men and women worldwide. Aberrantly expressed …

Co-delivery of insulin-like growth factor 1 receptor specific siRNA and doxorubicin using chitosan-based nanoparticles enhanced anticancer efficacy in A549 lung …

H Shali, M Shabani, F Pourgholi… - Artificial Cells …, 2018 - Taylor & Francis
Here, we investigated the effects of dual delivery of IGF-1R siRNA and doxorubicin by
chitosan nanoparticles on viability of A549 lung cancer cells line by utilization of MTT and …

Tumor-targeting magnetic lipoplex delivery of short hairpin RNA suppresses IGF-1R overexpression of lung adenocarcinoma A549 cells in vitro and in vivo

C Wang, C Ding, M Kong, A Dong, J Qian… - Biochemical and …, 2011 - Elsevier
Liposomal magnetofection potentiates gene transfection by applying a magnetic field to
concentrate magnetic lipoplexes onto target cells. Magnetic lipoplexes are self-assembling …

BMS-754807 is cytotoxic to non-small cell lung cancer cells and enhances the effects of platinum chemotherapeutics in the human lung cancer cell line A549

SE Franks, RA Jones, R Briah, P Murray… - BMC research …, 2016 - Springer
Background Despite advances in targeted therapy for lung cancer, survival for patients
remains poor and lung cancer remains the leading cause of cancer-related deaths …