In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

The prefrontal cortex (PFC) is deeply involved in higher brain functions, many of which are
altered in psychiatric conditions. The PFC exerts a top-down control of most cortical and …

Generalized anxiety disorder (GAD), the most frequently diagnosed form of anxiety, is
usually treated by cognitive-behavioural approaches or medication; in particular …

Serotonin (5-HT) 5-HT2C receptor (5-HT2CR) is recognized as a critical mediator of
diseaserelated pathways and behaviors based upon actions in the central nervous system …

Classic hallucinogens share pharmacology as serotonin 5-HT2A, 5-HT2B, and 5-HT2C
receptor agonists. Unique among most other Schedule 1 drugs, they are generally non …

Recent, well-controlled–albeit small-scale–clinical trials show that serotonergic
psychedelics, including psilocybin and lysergic acid diethylamide, possess great promise for …

Recently, a growing number of reports have indicated a positive effect of hallucinogenic-
based therapies in different neuropsychiatric disorders. However, hallucinogens belonging …

Ethnopharmacological relevance Cananga odorata essential oil, known as ylang-ylang
essential oil (YYO), was commonly used in the aromatherapy for relaxation and mood …

The synuclein family consists of α-, β-, and γ-Synuclein (α-Syn, β-Syn, and γ-Syn) expressed
in the neurons and concentrated in synaptic terminals. While α-Syn is at the center of interest …

Classical psychedelic drugs are thought to increase excitability of pyramidal cells in
prefrontal cortex via activation of serotonin 2 A receptors (5-HT2 A Rs). Here, we instead find …