Novel 4-(2-arylidenehydrazineyl) thienopyrimidine derivatives as anticancer EGFR inhibitors: Design, synthesis, biological evaluation, kinome selectivity and in silico …
HA Elsebaie, EA El-Bastawissy, KM Elberembally… - Bioorganic …, 2023 - Elsevier
The current study discovered fifteen new thieno [2, 3-d] pyrimidine derivatives with potential
anticancer action, including 5a-l, 6, and 7a-b. Results from the NCI screening revealed that …
anticancer action, including 5a-l, 6, and 7a-b. Results from the NCI screening revealed that …
Identification of 3‐(5‐cyano‐6‐oxo‐pyridin‐2‐yl) benzenesulfonamides as novel anticancer agents endowed with EGFR inhibitory activity
MA Shaldam, AF Khalil, H Almahli… - Archiv der …, 2024 - Wiley Online Library
Abstract New 5‐cyano‐6‐oxo‐pyridine‐based sulfonamides (6a–m and 8a–d) were
designed and synthesized to potentially inhibit both the epidermal growth factor receptor …
designed and synthesized to potentially inhibit both the epidermal growth factor receptor …
[HTML][HTML] Multi-task aquatic toxicity prediction model based on multi-level features fusion
X Yang, J Sun, B Jin, Y Lu, J Cheng, J Jiang… - Journal of Advanced …, 2024 - Elsevier
Introduction With the escalating menace of organic compounds in environmental pollution
imperiling the survival of aquatic organisms, the investigation of organic compound toxicity …
imperiling the survival of aquatic organisms, the investigation of organic compound toxicity …
[HTML][HTML] New perspectives on the potential of tetrandrine in the treatment of non-small cell lung cancer: bioinformatics, Mendelian randomization study and …
J Luo, X Mo, D Hu, Y Li, M Xu - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Background: Although there are numerous treatment methods for NSCLC, long-term survival
remains a challenge for patients. The objective of this study is to investigate the role and …
remains a challenge for patients. The objective of this study is to investigate the role and …
Elucidating the active compound profile and mechanisms of Dendrophthoe pentandra on colorectal cancer: LCMS/MS identification and network pharmacology …
R Mutiah, E Rachmawati… - Journal of Applied …, 2024 - repository.uin-malang.ac.id
Colorectal cancer (CRC) is the second leading cause of death worldwide, and its incidence
has significantly increased over the past decade. Although the herbal plant Dendrophthoe …
has significantly increased over the past decade. Although the herbal plant Dendrophthoe …
[HTML][HTML] Exploring the anticancer potential of Eleutherine bulbosa: A systematic network pharmacology study on lung cancer
R Mutiah, E Rachmawati - Journal of Advanced Pharmaceutical …, 2024 - journals.lww.com
Chemotherapy application in lung cancer patients has several side effects and shows lower
effectiveness due to chemoresistance. Although Eleutherine bulbosa (Mill.) Urb.(EBE) elicit …
effectiveness due to chemoresistance. Although Eleutherine bulbosa (Mill.) Urb.(EBE) elicit …