Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected
persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg) …

Cryptococcal meningitis is a devastating brain infection cause by encapsulated yeasts of the
Cryptococcus genus. Exposure, through inhalation, is likely universal by adulthood, but …

The genus Cryptococcus contains two primary species complexes that are significant
opportunistic human fungal pathogens: C. neoformans and C. gattii. In humans …

Cryptococcal meningitis is a leading cause of morbidity and mortality globally, especially in
people with advanced HIV disease. Cryptococcal meningitis is responsible for nearly 20% of …

Central nervous system (CNS) cryptococcosis in non-HIV infected patients affects solid
organ transplant (SOT) recipients, patients with malignancy, rheumatic disorders, other …

Neurological conditions associated with HIV remain major contributors to morbidity and
mortality and are increasingly recognized in the aging population on long-standing …

In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-
related cryptococcal disease. Two strategies are recommended to reduce the high mortality …

Background Patients without human immunodeficiency virus (HIV) are increasingly
recognized as being at risk for cryptococcosis. Knowledge of characteristics of …

Cryptococcal infections burden the immunocompromised population with unacceptably high
morbidity and mortality. This population includes HIV-infected individuals and those …