The role of protein SUMOylation in human hepatocellular carcinoma: A potential target of new drug discovery and development

H Yuan, Y Lu, YT Chan, C Zhang, N Wang, Y Feng - Cancers, 2021 - mdpi.com
Simple Summary The small ubiquitin-like modifier is a highly conserved post-translational
modification protein, mainly found in eukaryotes. Recently, studies have shown that …

[HTML][HTML] Hepatitis C virus/human T lymphotropic virus 1/2 co-infection: Regional burden and virological outcomes in people who inject drugs

E Castro, E Roger - World journal of virology, 2016 - ncbi.nlm.nih.gov
This review analyses current data concerning co-infection with hepatitis C virus (HCV) and
human T lymphotropic virus (HTLV)-1/2 in people who inject drugs (PWID), with a particular …

A novel one-class SVM based negative data sampling method for reconstructing proteome-wide HTLV-human protein interaction networks

S Mei, H Zhu - Scientific reports, 2015 - nature.com
Protein-protein interaction (PPI) prediction is generally treated as a problem of binary
classification wherein negative data sampling is still an open problem to be addressed. The …

HTLV-1 tax functions as a ubiquitin E3 ligase for direct IKK activation via synthesis of mixed-linkage polyubiquitin chains

C Wang, W Long, C Peng, L Hu, Q Zhang, A Wu… - PLoS …, 2016 - journals.plos.org
The HTLV-1 oncoprotein Tax plays a key role in CD4+ T cell transformation by promoting
cell proliferation and survival, mainly through permanent activation of the NK-κB pathway …

F508del-CFTR rescue: a matter of cell stress response

E Nieddu, B Pollarolo, L Merello… - Current …, 2013 - ingentaconnect.com
Cystic fibrosis (CF) is a common inherited fatal disease affecting 70,000 people worldwide,
with a median predicted age of survival of approximately 38 years. The deletion of …

First report of HTLV-1 truncated p12 protein in Brazil

C Rosadas, ACP Vicente, L Zanella, MJ Cabral-Castro… - Virulence, 2017 - Taylor & Francis
HTLV-1 infects approximately 5-10 millions of individuals in the world and the majority of
them remain lifelong asymptomatic carriers (AC). However, up to 5% of HTLV-1 patients may …

Diffuse Papular Eruption

AL Ross, CR Blieden, J Alonso-Llamazares - JAMA dermatology, 2015 - jamanetwork.com
Discussion Adult T-cell leukemia/lymphoma is a peripheral T-cell neoplasm caused by
HTLV-1. Four clinical subtypes of ATLL have been described: acute, smoldering, chronic …

Efecto de proteínas secretadas de linfocitos infectados con HTLV-I sobre la fosforilación de proteínas motoras en células PC12 como modelo de cultivo neuronal

MM Rivera Báez - 2013 - repositorio.uchile.cl
El virus HTLV-I (Virus Linfotrópico humano Tipo I) es el agente etiológico de dos patologías
principales, la Mielopatía asociada al HTLV-I/Paraparesia Espástica Tropical (HAM/TSP) …

[引用][C] 人T 细胞白血病1 型病毒Tax 蛋白对核因子κB 活性的影响

刘喜红, 牛志国, 王辉 - 新乡医学院学报, 2015