Active metabolites combination therapies: towards the next paradigm for more efficient and more scientific Chinese medicine

Q Gao, H Wu, M Chen, X Gu, Q Wu, T Xie… - Frontiers in …, 2024 - frontiersin.org
Traditional Chinese medicine (TCM) formulae have been studied extensively in various
human diseases and have proven to be effective due to their multi-component, multi-target …

Cefoperazone/sulbactam: New composites against multiresistant gram negative bacteria?

YH Ku, WL Yu - Infection, Genetics and Evolution, 2021 - Elsevier
Sulbactam, a class A β-lactamase inhibitor, added to cefoperazone either at a fixed 8 mg/L
level of sulbactam or at a level of fixed cefoperazone: sulbactam ratio (2: 1) would constitute …

Sulbactam Enhances in vitro Activity of β-Lactam Antibiotics Against Acinetobacter baumannii

L Wang, Y Chen, R Han, Z Huang… - Infection and Drug …, 2021 - Taylor & Francis
Purpose To evaluate in vitro activities of β-lactam antibiotics alone and in combination with
sulbactam at different ratios against Acinetobacter baumannii clinical strains from China …

Clinical efficacy of cefoperazone-sulbactam versus piperacillin-tazobactam in the treatment of hospital-acquired pneumonia and ventilator-associated pneumonia

CH Chen, CY Tu, WC Chen, LK Kuo… - Infection and Drug …, 2021 - Taylor & Francis
Objective The aim of this study was to compare the usefulness of cefoperazone-sulbactam
and that of piperacillin-tazobactam in the treatment of hospital-acquired pneumonia (HAP) …

A rare bacteremia caused by Fannyhessea vaginae in a pregnant woman: case report and literature review

P Liu, L Wang, R Li, X Chen - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Bloodstream infection caused by anaerobic microorganisms continues to be associated with
a high mortality risk, necessitating a rapid diagnosis and an appropriate treatment. As an …

Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii

RR McCarthy, GJ Larrouy-Maumus… - … : Infection and Immunity, 2021 - Springer
The discovery of penicillin over 90 years ago and its subsequent uptake by healthcare
systems around the world revolutionised global health. It marked the beginning of a golden …

In vitro activity of cefoperazone and cefoperazone-sulbactam against carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa

CC Lai, CC Chen, YC Lu, YC Chuang… - Infection and drug …, 2018 - Taylor & Francis
Background This study aimed to investigate the in vitro activity of cefoperazone–sulbactam
against carbapenem-resistant Acinetobacter baumannii and Pseudomonas aeruginosa, and …

Study on Demethoxycurcumin as a Promising Approach to Reverse Methicillin-Resistance of Staphylococcus aureus

QQ Li, OH Kang, DY Kwon - International Journal of Molecular Sciences, 2021 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) has always been a threatening
pathogen. Research on phytochemical components that can replace antibiotics with limited …

Cefepime/sulbactam as an enhanced antimicrobial combination therapy for the treatment of MDR Gram-negative infections

DW Wareham, MHFA Momin, LM Phee… - Journal of …, 2020 - academic.oup.com
Abstract Background β-Lactam (BL)/β-lactamase inhibitor (BLI) combinations are widely
used for the treatment of Gram-negative infections. Cefepime has not been widely studied in …

Efficacy and safety of cefoperazone-sulbactam in empiric therapy for febrile neutropenia: A systemic review and meta-analysis

SH Lan, SP Chang, CC Lai, LC Lu, HJ Tang - Medicine, 2020 - journals.lww.com
Purpose: This meta-analysis assessed the clinical efficacy and safety of cefoperazone-
sulbactam for empiric therapy febrile neutropenia. Methods: The PubMed, Web of Science …