Towards real-world generalizability of a circuit for action-stopping

R Hannah, AR Aron - Nature Reviews Neuroscience, 2021 - nature.com
Two decades of cross-species neuroscience research on rapid action-stopping in the
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …

[HTML][HTML] The brain-body disconnect: A somatic sensory basis for trauma-related disorders

BE Kearney, RA Lanius - Frontiers in neuroscience, 2022 - frontiersin.org
Although the manifestation of trauma in the body is a phenomenon well-endorsed by
clinicians and traumatized individuals, the neurobiological underpinnings of this …

[HTML][HTML] Behavioral decomposition reveals rich encoding structure employed across neocortex in rats

B Mimica, T Tombaz, C Battistin, JG Fuglstad… - Nature …, 2023 - nature.com
The cortical population code is pervaded by activity patterns evoked by movement, but it
remains largely unknown how such signals relate to natural behavior or how they might …

[HTML][HTML] The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain

A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …

[HTML][HTML] Freezing of gait in Parkinson's disease: pathophysiology, risk factors and treatments

C Gao, J Liu, Y Tan, S Chen - Translational neurodegeneration, 2020 - Springer
Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …

Sensorimotor anatomy of gait, balance, and falls

CD MacKinnon - Handbook of clinical neurology, 2018 - Elsevier
The review demonstrates that control of posture and locomotion is provided by systems
across the caudal-to-rostral extent of the neuraxis. A common feature of the neuroanatomic …

[HTML][HTML] A roadmap to inform development, validation and approval of digital mobility outcomes: the Mobilise-D approach

L Rochester, C Mazzà, A Mueller, B Caulfield… - Digital …, 2020 - karger.com
Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a
pressing need for tools to facilitate remote visits and monitoring. Digital health technology …

Freezing of gait in Parkinson's disease reflects a sudden derangement of locomotor network dynamics

NG Pozzi, A Canessa, C Palmisano, J Brumberg… - Brain, 2019 - academic.oup.com
Freezing of gait is a disabling symptom of Parkinson's disease that causes a paroxysmal
inability to generate effective stepping. The underlying pathophysiology has recently …

A meta-analysis: Parkinson's disease and dual-task walking

TE Raffegeau, LM Krehbiel, N Kang, FJ Thijs… - Parkinsonism & related …, 2019 - Elsevier
A growing body of literature has reported the effects of dual tasks on gait performance in
people with Parkinson's disease (PD). The purpose of this meta-analysis was to synthesize …

[HTML][HTML] Measuring gait speed to better identify prodromal dementia

G Grande, F Triolo, A Nuara, AK Welmer… - Experimental …, 2019 - Elsevier
Slow gait speed has been shown to predict incident dementia and cognitive decline in older
individuals. We aimed to summarize the evidence concerning the association of slow gait …