Towards real-world generalizability of a circuit for action-stopping
Two decades of cross-species neuroscience research on rapid action-stopping in the
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …
[HTML][HTML] The brain-body disconnect: A somatic sensory basis for trauma-related disorders
BE Kearney, RA Lanius - Frontiers in neuroscience, 2022 - frontiersin.org
Although the manifestation of trauma in the body is a phenomenon well-endorsed by
clinicians and traumatized individuals, the neurobiological underpinnings of this …
clinicians and traumatized individuals, the neurobiological underpinnings of this …
[HTML][HTML] Behavioral decomposition reveals rich encoding structure employed across neocortex in rats
The cortical population code is pervaded by activity patterns evoked by movement, but it
remains largely unknown how such signals relate to natural behavior or how they might …
remains largely unknown how such signals relate to natural behavior or how they might …
[HTML][HTML] The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain
A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …
implications. Clinical and experimental studies on aging have uncovered numerous …
[HTML][HTML] Freezing of gait in Parkinson's disease: pathophysiology, risk factors and treatments
C Gao, J Liu, Y Tan, S Chen - Translational neurodegeneration, 2020 - Springer
Background Freezing of gait (FOG) is a common, disabling symptom of Parkinson's disease
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …
(PD), but the mechanisms and treatments of FOG remain great challenges for clinicians and …
Sensorimotor anatomy of gait, balance, and falls
CD MacKinnon - Handbook of clinical neurology, 2018 - Elsevier
The review demonstrates that control of posture and locomotion is provided by systems
across the caudal-to-rostral extent of the neuraxis. A common feature of the neuroanatomic …
across the caudal-to-rostral extent of the neuraxis. A common feature of the neuroanatomic …
[HTML][HTML] A roadmap to inform development, validation and approval of digital mobility outcomes: the Mobilise-D approach
Health care has had to adapt rapidly to COVID-19, and this in turn has highlighted a
pressing need for tools to facilitate remote visits and monitoring. Digital health technology …
pressing need for tools to facilitate remote visits and monitoring. Digital health technology …
Freezing of gait in Parkinson's disease reflects a sudden derangement of locomotor network dynamics
Freezing of gait is a disabling symptom of Parkinson's disease that causes a paroxysmal
inability to generate effective stepping. The underlying pathophysiology has recently …
inability to generate effective stepping. The underlying pathophysiology has recently …
A meta-analysis: Parkinson's disease and dual-task walking
TE Raffegeau, LM Krehbiel, N Kang, FJ Thijs… - Parkinsonism & related …, 2019 - Elsevier
A growing body of literature has reported the effects of dual tasks on gait performance in
people with Parkinson's disease (PD). The purpose of this meta-analysis was to synthesize …
people with Parkinson's disease (PD). The purpose of this meta-analysis was to synthesize …
[HTML][HTML] Measuring gait speed to better identify prodromal dementia
Slow gait speed has been shown to predict incident dementia and cognitive decline in older
individuals. We aimed to summarize the evidence concerning the association of slow gait …
individuals. We aimed to summarize the evidence concerning the association of slow gait …