Cardiovascular imaging has become an indispensable tool for patient diagnosis and follow
up. Probably the wide clinical applications of imaging are due to the possibility of a detailed …

Aging is a progressive decline of body function, during which many tissues accumulate few
cells with high levels of deleted mitochondrial DNA (mtDNA), leading to a defect of …

Cardiovascular magnetic resonance (CMR) imaging has become an accurate and versatile
imaging modality to visualize the cardiovascular system in normal or abnormal conditions. In …

Aims SUMO-specific protease 1 (SENP1) removes SUMO from proteins and plays important
roles in the regulation of multiple cellular signalling pathways. However, little is known about …

Recent studies have revealed an important role for LTBP-4 in elastogenesis. Its mutational
inactivation in humans causes autosomal recessive cutis laxa type 1C (ARCL1C), which is a …

MRI has been proven to be an accurate method for noninvasive assessment of cardiac
function. One of the current limitations of cardiac MRI is that it is time consuming. Therefore …

Background Clinical two-dimensional (2D) and clinical three-dimensional echocardiography
are validated against cardiac magnetic resonance imaging (CMR), the gold standard for left …

Background Renal artery stenosis (RAS) promotes hypertension and cardiac dysfunction.
The 2-kidney, 1-clip mouse model in many ways resembles RAS in humans and is …

Cardiac cell therapy with mesenchymal stem cells (MSCs) represents a promising treatment
approach for endstage heart failure. However, little is known about the underlying …

Transgenic and gene knockout rodent models are primordial to study pathophysiological
processes in cardiovascular research. Over time, cardiac MRI has become a gold standard …