Aggressive myeloid leukemia formation is directed by the Musashi 2/Numb pathway

LN Griner, GW Reuther - Cancer biology & therapy, 2010 - Taylor & Francis
Chronic myeloid leukemia (CML) progresses from a chronic phase to a deadly blast crisis
phase. While it is known that BCR-ABL initiates the disease and that secondary molecular …

[PDF][PDF] Gene expression profiling for the diagnosis and prognosis of acute myeloid leukaemia

K Mills - Front Biosci, 2008 - article.imrpress.com
Acute myeloid leukaemia (AML) is a heterogeneous disease covering a range of
morphological lineages and differentiation stages, but also has number of recurrent …

Analysis of translocations that involve the NUP98 gene in patients with 11p15 chromosomal rearrangements

YN Kobzev, J Martinez‐Climent, S Lee… - Genes …, 2004 - Wiley Online Library
The NUP98 gene has been reported to be fused with at least 15 partner genes in leukemias
with 11p15 translocations. We report the results of screening of cases with cytogenetically …

[HTML][HTML] Chromosome t (7; 11)(p15; p15) translocation in acute myeloid leukemia coexisting with multilineage dyspoiesis and mutations in NRAS and WT1: A case …

J Yang, X Lyu, X Zhu, X Meng, W Zuo… - Oncology …, 2017 - spandidos-publications.com
Abstract The chromosomal translocation t (7; 11)(p15; p15) and the resulting nucleoporin 98-
homeobox A9 (NUP98-HOXA9) gene fusion is rare but recurrent genetic abnormity in acute …

[PDF][PDF] Clinical implications and biochemical understanding of high plasma vitamin B12 levels

JFH Arendt - 2016 - kea.au.dk
Clinical implications and biochemical understanding of high plasma vitamin B12 levels Johan
Frederik Håkonsen Arendt Page 1 Clinical implications and biochemical understanding of high …

Neutrophil alkaline phosphatase in childhood blood diseases

久保田優, 宇佐美郁哉 - 日本小児血液学会雑誌, 2006 - jlc.jst.go.jp
Neutrophil alkaline phosphatase (NAP) activity was assessed cytochemically in 59 pediatric
patients with various types of blood diseases. The mean±standard deviation of the NAP …

[HTML][HTML] Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia

K Spinler, M Hamilton, J Bajaj, Y Shima, E Diaz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Myeloid leukemias, diseases marked by aggressiveness and poor outcomes, are frequently
triggered by oncogenic translocations. In the case of chronic myelogenous leukemia (CML) …

GENETIC AND GENOMICS IN CLINICAL HEMATOLOGY, III: ACUTE LEUKEMIAS

K Mills - Genomic Medicine: Principles and Practice, 2014 - books.google.com
Acute myeloid leukemia (AML) is a genetically heterogeneous disorder characterized by
arrest of differentiation in the myeloid lineage coupled with an accumulation of immature …

Hematological Malignancies: The Paradigm of Acute Myeloid Leukemia

KI Mills, A Burnett - Genomics and Clinical Medicine, 2008 - books.google.com
A cute myeloid leukemia (AML) is a clinically and molecular heterogeneous set of
hematopoietic disorders (Lowenberg et al., 1999) which account for 77% of acute leukemia …

[引用][C] RT-PCR 方法检测白血病中NUP98-HOX 融合基因的初步研究

张琰, 李玲, 温丙昭, 林仁勇, 曹旭, 王宁, 哈力达… - 中国实验血液学杂志, 2005