Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Unaccustomed exercise consisting of eccentric (ie, lengthening) muscle contractions often
results in muscle damage characterized by ultrastructural alterations in muscle tissue …

Exercise stimulates the release of proteins with autocrine, paracrine, or endocrine functions
produced in skeletal muscle, termed myokines. Based on the current state of knowledge, the …

Cytokines are important mediators of various aspects of health and disease, including
appetite, glucose and lipid metabolism, insulin sensitivity, skeletal muscle hypertrophy and …

Eccentric contractions, characterized by the lengthening of the muscle-tendon complex,
present several unique features compared with other types of contractions, which may lead …

The integrity and composition of the tumour microenvironment (TME) is highly plastic,
undergoing constant remodelling in response to instructive signals derived from alterations …

Increase in the practice of sport by more and more numerous people in the Western
countries is associated with an increase in muscle injuries, and in demand for improving …

Strenuous exercise is a potent stimulus to induce beneficial skeletal muscle adaptations,
ranging from increased endurance due to mitochondrial biogenesis and angiogenesis, to …

Sarcopenia is characterized by loss of muscle and reduction in muscle strength that
contributes to higher mortality rate and increased incidence of fall and hospitalization in the …

Mechanistic insights into the molecular events by which exercise enhances the skeletal
muscle phenotype are lacking, particularly in the context of type 2 diabetes. Here, we …