Only 30% of embryos from in vitro fertilized oocytes successfully implant and develop to
term, leading to repeated transfer cycles. To reduce time-to-pregnancy and stress for …

In ungulates, early embryonic development differs dramatically from that of mice and
humans and is characterized by an extended period of pre-and peri-implantation …

STUDY QUESTION Can we separate embryos cultured under either 7% or 20% oxygen
atmospheres by measuring their metabolic heterogeneity? SUMMARY ANSWER Metabolic …

Purpose Vitrification permits long-term banking of oocytes and embryos. It is a technically
challenging procedure requiring direct handling and movement of cells between potentially …

The influence of in vitro maturation (IVM) in oocytes is still not totally understood. The aim of
this study was to determine the influence of IVM on the metabolism and homeostasis of …

Cellular metabolism is a key regulator of energetics, cell growth, regeneration, and
homeostasis. Spatially mapping the heterogeneity of cellular metabolic activity is of great …

In vitro embryo production (IVEP) is an extremely important tool for genetic improvement in
livestock and it is the biotechnology that has grown the most recently. However, multiple …

Oocyte/embryo selection methodologies are either invasive or noninvasive and can be
applied at various stages of development from the oocyte to cleaved embryos and up to the …

The preimplantation embryo is extraordinarily sensitive to environmental signals and events
such that perturbations can alter embryo metabolism and program an altered developmental …

A preimplantation embryo exists independent of blood supply, and relies on energy sources
from its in vivo environment (eg, oviduct and uterine fluid) to sustain its development. The …