Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

The final decision to accept an organ for transplantation remains a subjective one. With
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …

Background. The optimal method of oxygen delivery to donor kidneys during ex vivo
machine perfusion has not been established. We have recently reported the beneficial …

The recent advances in machine perfusion (MP) technology involve settings ranging
between hypothermic, subnormothermic, and normothermic temperatures. Tissue level …

The use of blood for normothermic and subnormothermic kidney preservation hinders the
translation of these approaches and promising therapeutics. This study evaluates whether …

Ex vivo machine perfusion (EVMP) is an emerging technique for preserving explanted solid
organs with primary application in allogeneic organ transplantation. EVMP has been …

Background. The ideal preservation temperature for donation after circulatory death kidney
grafts is unknown. We investigated whether subnormothermic (22 C) ex vivo kidney machine …

The growing disparity between the demand for transplants and the available donor supply,
coupled with an aging donor population and increasing prevalence of chronic diseases …

Cold preservation is the standard of care for renal grafts. However, research on alternatives
like perfusion at higher temperatures and supplementing preservation solutions with …

The increasing number of patients on the kidney transplant waiting list underlines the need
to expand the donor pool and improve kidney graft utilization. By protecting kidney grafts …