Machine perfusion preservation versus static cold storage for deceased donor kidney transplantation

SJ Tingle, RS Figueiredo, JAG Moir… - Cochrane Database …, 2019 - cochranelibrary.com
Background Kidney transplantation is the optimal treatment for end‐stage kidney disease.
Retrieval, transport and transplant of kidney grafts causes ischaemia reperfusion injury. The …

[HTML][HTML] Delayed graft function in kidney transplant: risk factors, consequences and prevention strategies

C Ponticelli, F Reggiani, G Moroni - Journal of personalized medicine, 2022 - mdpi.com
Background. Delayed graft function is a frequent complication of kidney transplantation that
requires dialysis in the first week posttransplant. Materials and Methods. We searched for …

Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial

I Jochmans, A Brat, L Davies, HS Hofker… - The Lancet, 2020 - thelancet.com
Background Deceased donor kidneys are preserved in cold hypoxic conditions. Providing
oxygen during preservation might improve post-transplant outcomes, particularly for kidneys …

Systematic review and meta-analysis of hypothermic machine perfusion versus static cold storage of kidney allografts on transplant outcomes

JM O'callaghan, RD Morgan, SR Knight… - Journal of British …, 2013 - academic.oup.com
Background Adequate preservation of renal allografts for transplantation is important for
maintaining and improving transplant outcomes. There are two prevalent methods …

Hypothermic machine perfusion is superior to static cold storage in deceased donor kidney transplantation: A meta‐analysis

SJ Tingle, RS Figueiredo, JAG Moir… - Clinical …, 2020 - Wiley Online Library
Background There remains a lack of consensus on the optimal storage method for deceased
donor kidneys. This meta‐analysis compares storage with hypothermic machine perfusion …

Machine perfusion in organ transplantation: a tool for ex-vivo graft conditioning with mesenchymal stem cells?

D Van Raemdonck, A Neyrinck, F Rega… - Current opinion in …, 2013 - journals.lww.com
Machine perfusion of solid organs has regained much attention during the last decade. It
provides a new promising tool that may allow pretransplant ex-vivo assessment …

Strategies for an expanded use of kidneys from elderly donors

MJ Pérez-Sáez, N Montero, D Redondo-Pachón… - …, 2017 - journals.lww.com
The old-for-old allocation policy used for kidney transplantation (KT) has confirmed the
survival benefit compared to remaining listed on dialysis. Shortage of standard donors has …

Hypothermic machine perfusion of kidneys retrieved from standard and high‐risk donors

I Jochmans, JM O'Callaghan, J Pirenne… - Transplant …, 2015 - Wiley Online Library
Hypothermic machine perfusion (HMP) of kidneys is a long‐established alternative to static
cold storage and has been suggested to be a better preservation method. Today, as our …

[HTML][HTML] Maximizing kidneys for transplantation using machine perfusion: from the past to the future: A comprehensive systematic review and meta-analysis

AM Hameed, HC Pleass, G Wong, WJ Hawthorne - Medicine, 2016 - journals.lww.com
Background: The two main options for renal allograft preservation are static cold storage
(CS) and machine perfusion (MP). There has been considerably increased interest in MP …

[HTML][HTML] Machine perfusion of the liver: a review of clinical trials

N Serifis, R Matheson, D Cloonan, CG Rickert… - Frontiers in …, 2021 - frontiersin.org
Although efforts have been made by transplant centers to increase the pool of available
livers by extending the criteria of liver acceptance, this practice creates risks for recipients …