[HTML][HTML] Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
mechanisms by which ELA increases the risk for future psychopathology are still poorly …
The future of rodent models in depression research
Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …
burden of this debilitating disorder is anticipated to increase markedly over the coming …
[HTML][HTML] Substance P and pain chronicity
W Zieglgänsberger - Cell and tissue research, 2019 - Springer
Substance P (SP) is a highly conserved member of the tachykinin peptide family that is
widely expressed throughout the animal kingdom. The numerous members of the tachykinin …
widely expressed throughout the animal kingdom. The numerous members of the tachykinin …
[HTML][HTML] Animal models of PTSD: a challenge to be met
G Richter-Levin, O Stork, MV Schmidt - Molecular psychiatry, 2019 - nature.com
Recent years have seen increased interest in psychopathologies related to trauma
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …
exposure. Specifically, there has been a growing awareness to posttraumatic stress disorder …
[HTML][HTML] Impact of early life stress on reward circuit function and regulation
Early life stress–including experience of child maltreatment, neglect, separation from or loss
of a parent, and other forms of adversity–increases lifetime risk of mood, anxiety, and …
of a parent, and other forms of adversity–increases lifetime risk of mood, anxiety, and …
[HTML][HTML] Early life stress alters transcriptomic patterning across reward circuitry in male and female mice
Abuse, neglect, and other forms of early life stress (ELS) significantly increase risk for
psychiatric disorders including depression. In this study, we show that ELS in a postnatal …
psychiatric disorders including depression. In this study, we show that ELS in a postnatal …
What does not kill you makes you stronger: Entrepreneurs' childhood adversity, resilience, and career success
Childhood adversities, such as neglect, abuse, and poverty, lead to negative career
outcomes. Anecdotal stories of entrepreneurs, however, present a contrasting picture …
outcomes. Anecdotal stories of entrepreneurs, however, present a contrasting picture …
[HTML][HTML] Biological and psychological perspectives of resilience: is it possible to improve stress resistance?
H Liu, C Zhang, Y Ji, L Yang - Frontiers in human neuroscience, 2018 - frontiersin.org
The term “resilience” refers to the ability to adapt successfully to stress, trauma and
adversity, enabling individuals to avoid stress-induced mental disorders such as depression …
adversity, enabling individuals to avoid stress-induced mental disorders such as depression …
[HTML][HTML] Early life stress in rodents: animal models of illness or resilience?
S Murthy, E Gould - Frontiers in behavioral neuroscience, 2018 - frontiersin.org
Early life adversity is a known risk factor for mood and anxiety disorders in adult humans
(Heim et al., 2010; Huh et al., 2014; Rehan et al., 2017). Given the prevalence of both …
(Heim et al., 2010; Huh et al., 2014; Rehan et al., 2017). Given the prevalence of both …
[HTML][HTML] Environmental programming of susceptibility and resilience to stress in adulthood in male mice
Epidemiological evidence identifies early life adversity as a significant risk factor for the
development of mood disorders. Much evidence points to the role of early life experience in …
development of mood disorders. Much evidence points to the role of early life experience in …