B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies
MT Cencioni, M Mattoscio, R Magliozzi… - Nature Reviews …, 2021 - nature.com
Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …
Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) in which the immune system damages the protective insulation surrounding the nerve …
(CNS) in which the immune system damages the protective insulation surrounding the nerve …
Regulatory impairment in untreated Parkinson's disease is not restricted to Tregs: other regulatory populations are also involved
DD Álvarez-Luquín, A Arce-Sillas… - Journal of …, 2019 - Springer
Background Parkinson's disease (PD) is the second most common neurodegenerative
disease in the world. Various studies have suggested that the immune response plays a key …
disease in the world. Various studies have suggested that the immune response plays a key …
Regulatory B cells in infection, inflammation, and autoimmunity
S Dasgupta, S Dasgupta, M Bandyopadhyay - Cellular immunology, 2020 - Elsevier
Regulatory B (Breg) cells are characterized by differential expression of CD5 and CD1d in
mouse and CD24 and CD38 in human immune systems. The Breg family also includes LAG …
mouse and CD24 and CD38 in human immune systems. The Breg family also includes LAG …
Imbalance in pro-inflammatory and anti-inflammatory cytokines milieu in B cells of children with autism
B cells play multiple roles in preservation of healthy immune system including management
of immune responses by expression of pro-and anti-inflammatory cytokines. Several earlier …
of immune responses by expression of pro-and anti-inflammatory cytokines. Several earlier …
The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5
L Radomir, MP Kramer, M Perpinial… - Nature …, 2021 - nature.com
B cells have essential functions in multiple sclerosis and in its mouse model, experimental
autoimmune encephalomyelitis, both as drivers and suppressors of the disease. The …
autoimmune encephalomyelitis, both as drivers and suppressors of the disease. The …
[HTML][HTML] Therapies for multiple sclerosis targeting B cells
R Milo - Croatian medical journal, 2019 - ncbi.nlm.nih.gov
Increasing evidence suggests that B cells contribute both to the regulation of normal
autoimmunity and to the pathogenesis of immune mediated diseases, including multiple …
autoimmunity and to the pathogenesis of immune mediated diseases, including multiple …
Emerging role of innate B1 cells in the pathophysiology of autoimmune and neuroimmune diseases: Association with inflammation, oxidative and nitrosative stress …
B1 lymphocytes may be subdivided by CD5 and CD11b/Mac1 expression into B1a, with the
CD5 and CD11b/Mac1 phenotype, and B1b, which present as CD19 hi CD5 lo CD11b hi …
CD5 and CD11b/Mac1 phenotype, and B1b, which present as CD19 hi CD5 lo CD11b hi …
Regulatory B and T lymphocytes in multiple sclerosis: friends or foes?
GK Vasileiadis, E Dardiotis, A Mavropoulos… - Autoimmunity …, 2018 - Springer
Current clinical experience with immunomodulatory agents and monoclonal antibodies in
principle has established the benefit of depleting lymphocytic populations in relapsing …
principle has established the benefit of depleting lymphocytic populations in relapsing …
Neuroinflammation
D Mukhara, U Oh, GN Neigh - Handbook of Clinical Neurology, 2020 - Elsevier
Neuroinflammation is implicated in contributing to a variety of neurologic and somatic
illnesses including Alzheimer's disease (AD), Parkinson's disease (PD), and depression. In …
illnesses including Alzheimer's disease (AD), Parkinson's disease (PD), and depression. In …