Personalised virtual brain models in epilepsy

V Jirsa, H Wang, P Triebkorn, M Hashemi… - The Lancet …, 2023 - thelancet.com
Individuals with drug-resistant focal epilepsy are candidates for surgical treatment as a
curative option. Before surgery can take place, the patient must have a presurgical …

Harnessing the potential of machine learning and artificial intelligence for dementia research

JM Ranson, M Bucholc, D Lyall, D Newby… - Brain Informatics, 2023 - Springer
Progress in dementia research has been limited, with substantial gaps in our knowledge of
targets for prevention, mechanisms for disease progression, and disease-modifying …

Learning how network structure shapes decision-making for bio-inspired computing

M Schirner, G Deco, P Ritter - Nature Communications, 2023 - nature.com
To better understand how network structure shapes intelligent behavior, we developed a
learning algorithm that we used to build personalized brain network models for 650 Human …

BrainPy, a flexible, integrative, efficient, and extensible framework for general-purpose brain dynamics programming

C Wang, T Zhang, X Chen, S He, S Li, S Wu - Elife, 2023 - elifesciences.org
Elucidating the intricate neural mechanisms underlying brain functions requires integrative
brain dynamics modeling. To facilitate this process, it is crucial to develop a general-purpose …

Data-driven multiscale computational models of cortical and subcortical regions

S Ramaswamy - Current opinion in neurobiology, 2024 - Elsevier
Data-driven computational models of neurons, synapses, microcircuits, and mesocircuits
have become essential tools in modern brain research. The goal of these multiscale models …

[图书][B] The Computational Theory of Mind

M Colombo, G Piccinini - 2023 - cambridge.org
Summary The Computational Theory of Mind says that the mind is a computing system. It
has a long history going back to the idea that thought is a kind of computation. Its modern …

High-density exploration of activity states in a multi-area brain model

D Aquilué-Llorens, JS Goldman, A Destexhe - Neuroinformatics, 2024 - Springer
To simulate whole brain dynamics with only a few equations, biophysical, mesoscopic
models of local neuron populations can be connected using empirical tractography data …

Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness

AI Luppi, J Cabral, R Cofre, PAM Mediano, FE Rosas… - NeuroImage, 2023 - Elsevier
Disorders of consciousness are complex conditions characterised by persistent loss of
responsiveness due to brain injury. They present diagnostic challenges and limited options …

[HTML][HTML] Variations on the theme: focus on cerebellum and emotional processing

C Ciapponi, Y Li, DA Osorio Becerra… - Frontiers in Systems …, 2023 - frontiersin.org
The cerebellum operates exploiting a complex modular organization and a unified
computational algorithm adapted to different behavioral contexts. Recent observations …

The human digital twin brain in the resting state and in action

W Lu, Q Zheng, N Xu, J Feng… - arXiv preprint arXiv …, 2022 - arxiv.org
We simulate the human brain at the scale of up to 86 billion neurons, ie, digital twin brain
(DTB), which mimics certain aspects of its biological counterpart both in the resting state and …