The regeneration of bone remains one of the main challenges in the biomedical field, with
the need to provide more personalized and multifunctional solutions. The other persistent …

Tissue engineering is vital in treating injuries and restoring damaged tissues, aiming to
accelerate regeneration and optimize the complex healing process. In this study, multizonal …

Recent preclinical and clinical studies have focused on the active area of therapeutic
peptides due to their high potency, selectivity, and specificity in treating a broad range of …

Gene therapy is an intentional modulation of specific gene expression to hinder the disease
progress. Given the susceptibility of exogenous nucleic acids to the extracellular and …

Repair of bone defects exceeding a critical size has been always a big challenge in clinical
practice. Tissue engineering has exhibited great potential to effectively repair the defects …

Orthopedic bone plates, traditionally made from materials such as stainless steel or titanium
alloy, have been pivotal in treating fractures. However, the disparity in modulus between …

The regeneration of large bone defects is still demanding, requiring biocompatible scaffolds,
with osteoconductive and osteoinductive properties. This study aimed to assess the pre …

In equine medicine, assisted bone regeneration, including use of biomaterial substitutes like
hydroxyapatite (HAP), is crucial for addressing bone defects. To follow-up on the outcome of …

Targeted therapy represents a real opportunity to improve the health and lives of patients.
Developments in this field are confirmed by the fact that the global market for drug carriers …

Objectives: In order to ensure improved and accelerated bone regeneration, nano-
hydroxyapatite scaffolds are often enriched with different bioactive components to further …