Preventing breast and ovarian cancers in high‐risk BRCA1 and BRCA2 mutation carriers

IM Collins, RL Milne, PC Weideman… - Medical Journal of …, 2013 - Wiley Online Library
Objective: To estimate the prevalence of the use of cancer risk‐reducing measures among
Australian BRCA1 and BRCA2 mutation carriers. Design, setting and participants …

Cascaded Antitumor Therapy Excited by Dual Nanozymes Based on Energy Restriction and Photocatalysis

Z Li, J Bian, Z Xu, X Zhang, Y He, F Ye… - … Applied Materials & …, 2023 - ACS Publications
In nanocatalytic medicine, drugs can be transformed into toxic components through highly
selective and highly specific catalytic reactions in the tumor microenvironment, avoiding …

Cancer risk management decision making for BRCA+ women

TJ Leonarczyk, BE Mawn - Western Journal of Nursing …, 2015 - journals.sagepub.com
Women with pathogenic BRCA genetic mutations face high risks for cancer development.
Estimates vary among mutation carriers, with lifetime risks ranging from 41% to 90% for …

When do people deploy genetic determinism? A review pointing to the need for multi‐factorial theories of public utilization of scientific discourses

CM Condit - Sociology Compass, 2011 - Wiley Online Library
For over two decades, scholars in the humanities and social sciences have attended warily
and thoughtfully to the growing influence of biological and especially genetics‐based …

Time trends in uptake rates of risk-reducing mastectomy in Israeli asymptomatic BRCA1 and BRCA2 mutation carriers

L Galmor, R Bernstein-Molho, M Sklair-Levy… - Breast cancer research …, 2021 - Springer
Background The rate of risk-reducing bilateral mastectomy (RRBM) among cancer-free
Israeli female BRCA1/BRCA2 mutation carriers was reportedly 13% in 2010. Current RRBM …

Cost‐Effectiveness of Testing for Breast Cancer Susceptibility Genes

ML Holland, A Huston, K Noyes - Value in Health, 2009 - Wiley Online Library
Objectives: Genetic mutations in breast cancer susceptibility genes BRCA1/2 are associated
with an increased risk of breast/ovarian cancers. Cost‐effective preventive measures are …

International perspectives on genetic counseling and testing for breast cancer risk

B Meiser, C Gaff, C Julian-Reynier… - Breast …, 2007 - content.iospress.com
Familial cancer services have been developed in many countries in response to a rapidly
evolving demand for genetic counseling and testing for breast cancer risk. This article …

Contralateral risk-reducing mastectomy in BRCA1 and BRCA2 mutation carriers and other high-risk women in the Kathleen Cuningham Foundation Consortium for …

BE Kiely, MA Jenkins, JM McKinley… - Breast cancer research …, 2010 - Springer
The purpose of this study is to determine the prevalence and predictors of contralateral risk-
reducing mastectomy (CRRM) in Australasian women at high familial risk of a second …

[HTML][HTML] Variation in rates of uptake of preventive options by Canadian women carrying the BRCA1 or BRCA2 genetic mutation

KA Metcalfe, P Ghadirian, B Rosen, W Foulkes… - Open …, 2007 - ncbi.nlm.nih.gov
Background Women with a BRCA1 or BRCA2 genetic mutation have several options for
cancer prevention, including prophylactic surgery, chemoprevention and screening. In this …

Knowledge and use of finasteride for the prevention of prostate cancer

RJ Hamilton, LC Kahwati, LS Kinsinger - Cancer epidemiology, biomarkers & …, 2010 - AACR
Background: The knowledge about and use of chemopreventive agents for prostate cancer
by physicians has not been described. The Prostate Cancer Prevention Trial (PCPT) …