Genetic susceptibility testing for common complex disease is a practice that is currently in
clinical use. There are two types of gene mutations, and therefore, two varieties of genotype …

Background: Although there is growing consensus that clinically actionable genetic research
results should be returned to participants, research on recipients' experiences and best …

Advances in the genetic basis of kidney disease may mean that genetic testing is
increasingly important in reducing disease morbidity and mortality among patients …

Résumé Organised since 1990 in France, cancer genetics has been strengthened since
2003 by the programme" Plan Cancer" which resulted in an improvement of the organisation …

One of the primary purposes of genetic testing for mutations in the BRCA1 and BRCA2
genes in patients with familial breast/ovarian cancer has been to provide accurate advice to …

Purpose Women from BRCA mutation–positive families who do not carry the family-specific
mutation are generally at average cancer risk and therefore do not require intensive risk …

Objective To test whether the coping in deliberation (CODE) framework can be adapted to a
specific preference-sensitive medical decision: risk-reducing bilateral salpingo …

Background and Aims: Risk-reducing mastectomy of BRCA1 and BRCA2 gene mutation
carriers is known to significantly reduce lifetime risk of breast cancer. Our aim was to study …

Women carrying germline mutations in BRCA1 or BRCA2 have significantly increased
lifetime risks of breast and tubo-ovarian cancer. To manage the breast cancer risk women …

Background: Psychiatric genetics has had limited success in translational efforts. A thorough
understanding of the present state of translation in this field will be useful in the facilitation …