Fibrinolytic system and cancer: diagnostic and therapeutic applications

N Mahmood, SA Rabbani - International journal of molecular sciences, 2021 - mdpi.com
Fibrinolysis is a crucial physiological process that helps to maintain a hemostatic balance by
counteracting excessive thrombosis. The components of the fibrinolytic system are well …

[PDF][PDF] D-dimer and prothrombin fragment 1+ 2 predict venous thromboembolism in patients with cancer: results from the Vienna Cancer and Thrombosis Study

C Ay, R Vormittag, D Dunkler, R Simanek… - Journal of Clinical …, 2009 - researchgate.net
Purpose Venous thromboembolism (VTE) is a well-recognized complication of cancer.
Laboratory parameters might be useful to assess the VTE risk in patients with cancer. The …

Prognostic value of pretreatment plasma fibrinogen in patients with colorectal cancer: A systematic review and meta-analysis

M Li, Y Wu, J Zhang, L Huang, X Wu, Y Yuan - Medicine, 2019 - journals.lww.com
Background: Growing evidence showed that high pretreatment plasma fibrinogen could be
used as a potential prognostic marker in colorectal cancer (CRC). However, the conclusions …

Clinical significance of coagulation factors in operable colorectal cancer

S Lee, SJ Huh, SY Oh, MS Koh, SH Kim… - Oncology …, 2017 - spandidos-publications.com
Abnormal hemostasis in cancer patients has prev iously been studied. The primary objective
of the present study was to evaluate the association between preoperative hemostasis …

Cellular components contributing to the development of venous thrombosis in patients with pancreatic cancer

RAL Willems, C Biesmans, E Campello… - … in Thrombosis and …, 2023 - thieme-connect.com
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive type of cancer and has a poor
prognosis. Patients with PDAC are at high risk of developing thromboembolic events, which …

Membrane microvesicles: macromessengers in cancer disease and progression

D Castellana, F Toti, JM Freyssinet - Thrombosis research, 2010 - Elsevier
Thrombotic complications have been documented in patients with cancer, and associated
with tumor progression. Cancer patients have an increased level of circulating …

Plasma from cancer patients featuring a characteristic protein composition mediates protection against apoptosis

S Vejda, C Posovszky, S Zelzer, B Peter… - Molecular & Cellular …, 2002 - ASBMB
By comparative proteome analysis we searched for characteristic alterations of human
plasma accompanying neoplastic disease. We identified protein alterations in plasma of …

Elevated plasma levels of crosslinked fibrinogen gamma-chain dimer indicate cancer-related fibrin deposition and fibrinolysis

C Gerner, W Steinkellner, K Holzmann… - Thrombosis and …, 2001 - thieme-connect.com
Cancer-related fibrin deposition and fibrinolysis were investigated by two-dimensional gel
electrophoresis of human solid tumor and effusion specimen in addition to plasma samples …

Clinical and prognostic significance of coagulation assays in gastric cancer

F Tas, R Ciftci, L Kilic, M Serilmez, S Karabulut… - Journal of …, 2013 - Springer
Purpose Activation of coagulation and fibrinolysis is frequently found among cancer patients.
Such tumors are considered to be associated with a higher risk of invasion, metastases, and …

Melanotransferrin induces human melanoma SK-Mel-28 cell invasion in vivo

Y Bertrand, M Demeule, J Michaud-Levesque… - Biochemical and …, 2007 - Elsevier
The expression of melanotransferrin (MTf), a membrane-bound glycoprotein highly
expressed in melanomas, is correlated with tumor vascularization and progression …