Human papillomavirus molecular biology and disease association

J Doorbar, N Egawa, H Griffin… - Reviews in medical …, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) have evolved over millions of years to propagate
themselves in a range of different animal species including humans. Viruses that have co …

The biology and life-cycle of human papillomaviruses

J Doorbar, W Quint, L Banks, IG Bravo, M Stoler… - Vaccine, 2012 - Elsevier
Human papillomaviruses (HPVs) comprise a diverse group, and have different epithelial
tropisms and life-cycle strategies. Many HPVs are classified as low-risk, as they are only …

Human papillomavirus molecular biology

ME Harden, K Munger - Mutation Research/Reviews in Mutation Research, 2017 - Elsevier
Human papillomaviruses are small DNA viruses with a tropism for squamous epithelia. A
unique aspect of human papillomavirus molecular biology involves dependence on the …

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

JMM Walboomers, MV Jacobs… - The Journal of …, 1999 - Wiley Online Library
A recent report that 93 per cent of invasive cervical cancers worldwide contain human
papillomavirus (HPV) may be an underestimate, due to sample inadequacy or integration …

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

ML Gillison, WM Koch, RB Capone… - Journal of the …, 2000 - academic.oup.com
Background: High-risk human papillomaviruses (HPVs) are etiologic agents for anogenital
tract cancers and have been detected in head and neck squamous cell carcinomas …

Papillomavirus infections—a major cause of human cancers

H Zur Hausen - Biochimica et biophysica acta (BBA)-reviews on cancer, 1996 - Elsevier
The papillomavirus family represents a remarkably heterogeneous group of viruses. At
present, 77 distinct genotypes have been identified in humans and partial sequences have …

The natural history of cervical HPV infection: unresolved issues

CBJ Woodman, SI Collins, LS Young - Nature Reviews Cancer, 2007 - nature.com
The identification of high-risk human papillomavirus (HPV) types as a necessary cause of
cervical cancer offers the prospect of effective primary prevention and the possibility of …

[HTML][HTML] The E5 proteins

D DiMaio, LM Petti - Virology, 2013 - Elsevier
The E5 proteins are short transmembrane proteins encoded by many animal and human
papillomaviruses. These proteins display transforming activity in cultured cells and animals …

Viruses in human cancers

H Zur Hausen - Science, 1991 - science.org
Viruses may contribute to the development of human tumors by different mechanisms:
indirectly by inducing immunosuppression or by modifying the host cell genome without …

Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm

AP Cullen, R Reid, M Campion, AT Lörincz - Journal of virology, 1991 - Am Soc Microbiol
The integration of human papillomavirus (HPV) DNA into the human genome has been
generally accepted as a characteristic of malignant lesions. To gain a better understanding …