The emergence of form and function during mammalian embryogenesis is a complex
process that involves multiple regulatory levels. The foundations of the body plan are laid …

Gene regulatory networks and tissue morphogenetic events drive the emergence of shape
and function: the pillars of embryo development. Although model systems offer a window …

Remodelling of the human embryo at implantation is indispensable for successful
pregnancy. Yet it has remained mysterious because of the experimental hurdles that beset …

At implantation, with the acquisition of a receptive phenotype in the uterine epithelium, an
initial tenuous attachment of embryonic trophectoderm initiates reorganisation of epithelial …

BACKGROUND Successful embryo implantation is a complex process that requires the
coordination of a series of events, involving both the embryo and the maternal endometrium …

BACKGROUND Over the past few years, advances in molecular technologies have allowed
unprecedented mapping of epigenetic modifications in gametes and during early embryonic …

Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …

Bacteria colonize most of the human body, and the female genital tract is not an exception.
While the existence of a vaginal microbiota has been well established, the upper genital …

Abstract Development of the mammalian embryo begins with formation of the totipotent
zygote during fertilization. This initial cell is able to give rise to every embryonic tissue of the …

The" 14-day rule" for embryo research stipulates that experiments with intact human
embryos must not allow them to develop beyond 14 days or the appearance of the primitive …