[HTML][HTML] Aging of mesenchymal stem cell: machinery, markers, and strategies of fighting
Human mesenchymal stem cells (MSCs) are primary multipotent cells capable of
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …
differentiating into osteocytes, chondrocytes, and adipocytes when stimulated under …
[HTML][HTML] Antioxidant supplementation in oxidative stress-related diseases: What have we learned from studies on alpha-tocopherol?
FL Meulmeester, J Luo, LG Martens, K Mills… - Antioxidants, 2022 - mdpi.com
Oxidative stress has been proposed as a key contributor to lifestyle-and age-related
diseases. Because free radicals play an important role in various processes such as …
diseases. Because free radicals play an important role in various processes such as …
Effects of polyphenols and their metabolites on age-related diseases
Aging contributes to the progressive loss of cellular biological functions and increases the
risk of age-related diseases. Cardiovascular diseases, some neurological disorders and …
risk of age-related diseases. Cardiovascular diseases, some neurological disorders and …
[HTML][HTML] The role of cannabidiol in aging
B Ni, Y Liu, M Dai, J Zhao, Y Liang, X Yang… - Biomedicine & …, 2023 - Elsevier
Aging is usually considered a key risk factor associated with multiple diseases, such as
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …
neurodegenerative diseases, cardiovascular diseases and cancer. Furthermore, the burden …
Chemical synthesis and biochemical properties of cholestane-5α, 6β-diol-3-sulfonate: A non-hydrolysable analogue of cholestane-5α, 6β-diol-3β-sulfate
P de Médina, S Ayadi, R Soulès, B Payre… - The Journal of Steroid …, 2023 - Elsevier
Abstract Cholestane-3β, 5α, 6β-triol (CT) is a primary metabolite of 5, 6-epoxycholesterols
(5, 6-EC) that is catalyzed by the cholesterol-5, 6-epoxide hydrolase (ChEH). CT is a well …
(5, 6-EC) that is catalyzed by the cholesterol-5, 6-epoxide hydrolase (ChEH). CT is a well …
[HTML][HTML] Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications
Graphical abstract Abstract 7-Ketocholesterol (or 7-oxocholesterol) is an oxysterol
essentially formed by cholesterol autoxidation. It is often found at enhanced levels in the …
essentially formed by cholesterol autoxidation. It is often found at enhanced levels in the …
7β-Hydroxycholesterol and 7-ketocholesterol: New oxidative stress biomarkers of sarcopenia inducing cytotoxic effects on myoblasts and myotubes
Aging is a complex biological process which can be associated with skeletal muscle
degradation leading to sarcopenia. The aim of this study consisted i) to determine the …
degradation leading to sarcopenia. The aim of this study consisted i) to determine the …
[HTML][HTML] Oxidative status of ultra-processed foods in the Western diet
Ultra-processed foods (UPFs) have gained substantial attention in the scientific community
due to their surging consumption and potential health repercussions. In addition to their well …
due to their surging consumption and potential health repercussions. In addition to their well …
[HTML][HTML] 27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor
S Ayadi, S Friedrichs, R Soulès, L Pucheu… - Journal of Lipid …, 2023 - ASBMB
Abstract Oncosterone (6-oxo-cholestane-3β, 5α-diol; OCDO) is an oncometabolite and a
tumor promoter on estrogen receptor alpha-positive breast cancer (ER (+) BC) and triple …
tumor promoter on estrogen receptor alpha-positive breast cancer (ER (+) BC) and triple …
[HTML][HTML] Role of traditional Chinese medicine in age-related macular degeneration: exploring the gut microbiota's influence
Y Yu, Y Liu, Z Meng - Frontiers in Pharmacology, 2024 - frontiersin.org
The pathogenesis of age-related macular degeneration (AMD), a degenerative retinopathy,
remains unclear. Administration of anti-vascular endothelial growth factor agents …
remains unclear. Administration of anti-vascular endothelial growth factor agents …