Gastric cancer is the second most common cause of cancer-related deaths in the world, the
epidemiology of which has changed within last decades. A trend of steady decline in gastric …

Gastric cancer (GC) remains an important cause of cancer death worldwide with a high
mortality rate due to the fact that the majority of GC cases are diagnosed at an advanced …

Helicobacter pylori (H. pylori) infection is well known to be associated with the development
of precancerous lesions such as chronic atrophic gastritis (AG), or gastric intestinal …

Epigenetic mechanisms comprising DNA methylation, histone modifications, and noncoding
RNAs affect chromatin structure and regulate gene expression. These mechanisms control …

Background: We examined the levels of long non-coding RNAs (lncRNAs) in the plasma of
patients with gastric cancer to assess their clinical significance for diseases diagnosing and …

Introduction: Risk prediction of gastric cancers is important to implement appropriate
screening procedures. Although aberrant DNA methylation is deeply involved in gastric …

Wnt-5a is a representative ligand that activates a β-catenin-independent pathway in the Wnt
signaling. Although abnormal activation of β-catenin-dependent pathway is often observed …

Gastric cancer is classified into intestinal and diffuse types, the latter including a highly
malignant form, linitis plastica. A two-stage genome-wide association study (stage 1: 85,576 …

Gastric cancer (GC) is one of the most common malignancies worldwide. Genes expressed
only in cancer tissue will be useful molecular markers for diagnosis and may also be good …

Accumulation of aberrant DNA methylation in normal‐appearing gastric mucosae, mostly
induced by H. pylori infection, is now known to be deeply involved in predisposition to …