Developing nociceptor-selective treatments for acute and chronic pain

S Jayakar, J Shim, S Jo, BP Bean, I Singeç… - Science translational …, 2021 - science.org
Despite substantial efforts dedicated to the development of new, nonaddictive analgesics,
success in treating pain has been limited. Clinically available analgesic agents generally …

Postoperative pain management in enhanced recovery pathways

CK Cheung, JO Adeola, SS Beutler… - Journal of Pain …, 2022 - Taylor & Francis
Postoperative pain is a common but often inadequately treated condition. Enhanced
recovery pathways (ERPs) are increasingly being utilized to standardize perioperative care …

[HTML][HTML] Pharmacotherapeutic pain management in patients undergoing laparoscopic cholecystectomy: A review

B Jiang, S Ye - Advances in Clinical and Experimental …, 2022 - advances.umw.edu.pl
Laparoscopic cholecystectomy is widely performed because it results in a relatively easier
pain management and shorter hospital stay. Although postoperative pain following …

NSAIDs for Pain Control During the Peri-Operative Period of Hip Fracture Surgery: A Systematic Review

W Pommier, EM Minoc, PM Morice, P Lescure… - Drugs & Aging, 2024 - Springer
Background Hip fracture (HF) mostly affects older adults and is responsible for increased
morbidity and mortality. Non-steroidal anti-inflammatory drugs (NSAIDs) are part of the peri …

Adverse effects of nonsteroidal anti-inflammatory drugs in critically ill patients: A scoping review

JR Martin, M Yu, BL Erstad - American Journal of Health-System …, 2023 - academic.oup.com
Purpose Nonsteroidal anti-inflammatory drugs (NSAIDs) are often recommended as opioid-
sparing agents. The objective of this scoping review was to conduct a thorough search of the …

Single‐dose intravenous ibuprofen for acute postoperative pain in adults

MKC Ferguson, R Schumann… - Cochrane Database …, 2021 - cochranelibrary.com
Background Postoperative administration of non‐steroidal anti‐inflammatory drugs
(NSAIDs) reduces patient opioid requirements and, in turn, may reduce the incidence and …

Postoperative administration of ketorolac compared to other drugs for pain control after third molar surgery: A meta‐analysis of double‐blind, randomized, clinical trials

MA Isiordia‐Espinoza, ÁJ Alonso‐Castro… - British Journal of …, 2022 - Wiley Online Library
Aims The aim of this study was to evaluate the analgesic effectiveness and adverse
reactions of ketorolac in comparison with other drugs when administered postoperatively …

[PDF][PDF] A review on transdermal patches used as an anti-inflammatory agent

D Choudhury, KN Dutta, R Kalita - Asian Journal of Pharmaceutical …, 2021 - academia.edu
The transdermal drug delivery system is widely accepted due to its numerous advantages as
it is a non-invasive drug administration process with prolonged therapeutic effect, reduced …

Non-Opioid Analgesics and Adjuvants after Surgery in Adults with Obesity: Systematic Review with Network Meta-Analysis of Randomized Controlled Trials

M Carron, E Tamburini, F Linassi, T Pettenuzzo… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Managing postoperative pain in patients with obesity is challenging.
Although using a combination of pain relief methods is recommended for these patients, the …

In silico design of new ketorolac bioisosteres as anti-inflammatory agents

CD Gamarra-Sánchez, CN Rodriguez-Silva… - Journal of Applied …, 2024 - japsonline.com
Nonsteroidal anti-inflammatory drugs (NSAIDs) are over-the-counter drugs and one of the
most widely used pharmacological groups worldwide, their chronic use is limited due to their …