Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
[HTML][HTML] Cannabinoids in the landscape of cancer
N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …
Pharmacological data of cannabidiol-and cannabigerol-type phytocannabinoids acting on cannabinoid CB1, CB2 and CB1/CB2 heteromer receptors
Background Recent approved medicines whose active principles are Δ 9
Tetrahidrocannabinol (Δ 9-THC) and/or cannabidiol (CBD) open novel perspectives for …
Tetrahidrocannabinol (Δ 9-THC) and/or cannabidiol (CBD) open novel perspectives for …
Insights on the antiradical capacity and mechanism of phytocannabinoids: H-abstraction and electron transfer processes in physiological media and the influence of …
H Boulebd - Phytochemistry, 2023 - Elsevier
Phytocannabinoids are natural products primarily isolated from Cannabis sativa that exhibit
the typical C21 terpenophenolic skeleton. This class of compounds has been shown to be …
the typical C21 terpenophenolic skeleton. This class of compounds has been shown to be …
[HTML][HTML] Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic …
Traumatic brain injury is common, and often results in debilitating consequences. Even mild
traumatic brain injury leaves approximately 20% of patients with symptoms that persist for …
traumatic brain injury leaves approximately 20% of patients with symptoms that persist for …
[HTML][HTML] The pathophysiology and the therapeutic potential of cannabinoids in prostate cancer
Simple Summary Prostate cancer, after lung cancer, is the leading cause of death among
men. The incidence rate of prostate cancer varies worldwide between regions and …
men. The incidence rate of prostate cancer varies worldwide between regions and …
[HTML][HTML] Decoding the Postulated Entourage Effect of Medicinal Cannabis: What It Is and What It Isn't
C Christensen, M Rose, C Cornett, M Allesø - Biomedicines, 2023 - mdpi.com
The 'entourage effect'term was originally coined in a pre-clinical study observing
endogenous bio-inactive metabolites potentiating the activity of a bioactive …
endogenous bio-inactive metabolites potentiating the activity of a bioactive …
A Comparative In Vitro Study of the Neuroprotective Effect Induced by Cannabidiol, Cannabigerol, and Their Respective Acid Forms: Relevance of the 5-HT1A …
C Echeverry, G Prunell, C Narbondo… - Neurotoxicity …, 2021 - Springer
Previous preclinical studies have demonstrated that cannabidiol (CBD) and cannabigerol
(CBG), two non-psychotomimetic phytocannabinoids from Cannabis sativa, induce …
(CBG), two non-psychotomimetic phytocannabinoids from Cannabis sativa, induce …
[HTML][HTML] Similarities and differences upon binding of naturally occurring Δ9-tetrahydrocannabinol-derivatives to cannabinoid CB1 and CB2 receptors
I Raïch, R Rivas-Santisteban, A Lillo, J Lillo… - Pharmacological …, 2021 - Elsevier
We have here assessed, using Δ 9-tetrahydrocannabinol (Δ 9-THC) for comparison, the
effect of Δ 9-tetrahydrocannabinolic acid (Δ 9-THCA) and of Δ 9-tetrahydrocannabivarin (Δ9 …
effect of Δ 9-tetrahydrocannabinolic acid (Δ 9-THCA) and of Δ 9-tetrahydrocannabivarin (Δ9 …
Nanoparticle-based genetic transformation of Cannabis sativa
Cannabis sativa (Cannabis) is a multipurpose plant species consisting of specific lineages
that for centuries has either been artificially selected for the production of fiber or the …
that for centuries has either been artificially selected for the production of fiber or the …