Crosstalk between the gut microbiome and colonic motility in chronic constipation: potential mechanisms and microbiota modulation

R Pan, L Wang, X Xu, Y Chen, H Wang, G Wang… - Nutrients, 2022 - mdpi.com
Chronic constipation (CC) is a highly prevalent and burdensome gastrointestinal disorder.
Accumulating evidence highlights the link between imbalances in the gut microbiome and …

Functional oligosaccharide fermentation in the gut: Improving intestinal health and its determinant factors-A review

N Zhang, M Jin, K Wang, Z Zhang, NP Shah… - Carbohydrate Polymers, 2022 - Elsevier
The human intestine is characterized by an abundance of nutrients and a complex
microbiota that make crucial contributions to overall health. These nutrients facilitate the …

Nanocrystalline Cellulose Cures Constipation via Gut Microbiota Metabolism

M Wang, R Cha, W Hao, R Du, P Zhang, Y Hu… - ACS nano, 2022 - ACS Publications
Constipation can seriously affect the quality of life and increase the risk of colorectal cancer.
The present strategies for constipation therapy have adverse effects, such as causing …

Bifidobacterium longum relieves constipation by regulating the intestinal barrier of mice

L Wang, M Chai, J Wang, YU Qiangqing, G Wang… - Food & function, 2022 - pubs.rsc.org
Constipation is a major health concern worldwide, requiring effective and safe treatment
options. This study mainly focused on three species and nine strains of bifidobacteria from …

Xylooligosaccharides from corn cobs alleviate loperamide-induced constipation in mice via modulation of gut microbiota and SCFA metabolism

H Song, R Guo, X Sun, Y Kou, X Ma, Y Chen, L Song… - Food & Function, 2023 - pubs.rsc.org
This study aimed to optimize the structure and efficacy of xylooligosaccharides (XOSs) from
corn cobs in constipated mice. Structural analysis revealed that XOSs from corn cobs were …

Prebiotic activity of chitooligosaccharides and their ability to alleviate necrotizing enterocolitis in newborn rats

X Wei, L Yu, C Zhang, Y Ni, J Zhao, H Zhang… - Carbohydrate …, 2023 - Elsevier
Chitooligosaccharides (COS) have many bioactive functions and favorable prospects in the
fields of biomedicine and functional foods. In this study, COS was found to significantly …

Regulation of gut microbiota and intestinal metabolites by Poria cocos oligosaccharides improves glycolipid metabolism disturbance in high-fat diet-fed mice

L Zhu, C Ye, B Hu, H Xia, Q Bian, Y Liu, M Kong… - The Journal of …, 2022 - Elsevier
In this study, we aimed to explore the effect of Poria cocos oligosaccharides (PCO) on
glucolipid metabolism disorder. Based on a high-fat diet (HFD)-induced obese mouse …

Nondigestible functional oligosaccharides: enzymatic production and food applications for intestinal health

S Yang, C Wu, Q Yan, X Li… - Annual Review of Food …, 2023 - annualreviews.org
Nondigestible functional oligosaccharides are of particular interest in recent years because
of their unique prebiotic activities, technological characteristics, and physiological effects …

The role of carbohydrate intake on the gut microbiome: a weight of evidence systematic review

LP Mora-Flores, R Moreno-Terrazas Casildo… - Microorganisms, 2023 - mdpi.com
(1) Background: Carbohydrates are the most important source of nutritional energy for the
human body. Carbohydrate digestion, metabolism, and their role in the gut microbiota …

Chitosan oligosaccharides regulate the occurrence and development of enteritis in a human gut-on-a-chip

B Jing, K Xia, C Zhang, S Jiao, L Zhu, J Wei… - Frontiers in Cell and …, 2022 - frontiersin.org
Past studies on the protective effects of chitosan oligosaccharides (COS) on inflammatory
bowel disease (IBD) commonly rely on animal models, because traditional cell culture …