Polycyclic aromatic hydrocarbons (PAHs) are often detected in the environment and are
regarded as endocrine disruptors. We here designated mixtures of PAHs in the environment …

There has been increasing evidence pointing to the mitochondrial respiratory chain (MRC)
as a novel and important target for the actions of 17β-estradiol (E2) and estrogen receptors …

Benzo [a] pyrene (B a P), a five‐ring polycyclic aromatic hydrocarbon, is a well‐recognized
environmental pollutant. Coal‐processing waste products, petroleum sludge, asphalt …

The last decade witnessed extraordinary advances in “omics” methods, particularly
transcriptomics, proteomics and metabolomics, enabling toxicologists to integrate …

The term polycyclic organic matter (POM) defines a broad class of compounds that generally
includes all organic structures containing three or more fused aromatic rings. These …

Cancer cells display alterations in many cellular processes. One core hallmark of cancer is
the Warburg effect which is a glycolytic reprogramming that allows cells to survive and …

Chemical modifications of RNA molecules have gained increasing attention since evidence
emerged for their substantive roles in a range of biological processes, such as the stability …

Metastasis is the leading cause of deaths in patients with breast cancer. Benzo [a] pyrene is
a cumulative carcinogen and ubiquitous environmental pollutant with potent carcinogenic …

Polycyclic aromatic hydrocarbons (PAHs) are global contaminants of concern. Despite
several decades of research, their mechanisms of toxicity are not very well understood. Early …

Indiscriminate usage and mismanagement of chemicals in the agricultural and industrial
sectors have contaminated different environmental compartments. Exposure to these …