Neural tube defects (NTDs), including spina bifida and anencephaly, are severe birth
defects of the central nervous system that originate during embryonic development when the …

Background Neural tube defects (NTDs) are debilitating birth defects involving the central
nervous system (CNS). Despite recent advances, NTDs represent the second most common …

Objective To provide updated information on the pre-and post-conception use of oral folic
acid with or without a multivitamin/micronutrient supplement for the prevention of neural tube …

The worldwide incidence of neural tube defects (NTDs) ranges from 1.0 to 10.0 per 1,000
births with almost equal frequencies between two major categories: anencephaly and spina …

Within the last few years, knowledge about vitamins has increased dramatically. This new
edition of a bestseller presents comprehensive summaries that analyze the chemical …

Neural tube defects (NTDs) are common, severe congenital malformations whose causation
involves multiple genes and environmental factors. Although more than 200 genes are …

More evidence is available for maternal intake, absorption, distribution, tissue specific
concentrations, and pregnancy outcomes with folic acid (fortification/supplementation) …

Human populations use a variety of subsistence strategies to exploit an exceptionally broad
range of ecoregions and dietary components. These aspects of human environments have …

The clinical significance of periconceptional folic acid supplementation (FAS) in the
prevention of neonatal neural tube defects (NTDs) has been recognized for decades …

Spina bifida is among the phenotypes of the larger condition known as neural tube defects
(NTDs). It is the most common central nervous system malformation compatible with life and …