Network analytical tools are increasingly being applied to brain imaging maps of resting
metabolic activity (PET) or blood oxygenation-dependent signals (functional MRI) to …

Fluorine-containing heterocycles continue to receive considerable attention due to their
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …

Artificial intelligence (AI)-assisted PET imaging is emerging as a promising tool for the
diagnosis of Parkinson's disease (PD). We aim to systematically review the diagnostic …

Introduction There is currently no definitive diagnostic test for Parkinson's disease (PD) and
the current diagnostic procedure primarily relies on clinical manifestations. A hypointense …

Multiple system atrophy (MSA) is a rare neurodegenerative disease that is characterized by
neuronal loss and gliosis in multiple areas of the central nervous system including …

Background The clinical diagnosis of multiple system atrophy (MSA) is challenged by
overlapping features with Parkinson's disease (PD) and late‐onset ataxias. Additional …

Background In the current consensus diagnostic criteria, the diagnosis of probable multiple
system atrophy (MSA) is based solely on clinical findings, whereas neuroimaging findings …

Purpose To give a comprehensive literature overview of alterations in regional cerebral
glucose metabolism, measured using [18F] FDG PET, in conditions associated with …

Positron emission tomography (PET) allows for the in vivo assessment of early brain
functional and molecular changes in neurodegenerative conditions, representing a unique …

Background Quantitative analysis of brain positron-emission tomography (PET) depends on
structural segmentation, which can be time-consuming and operator-dependent when …