Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that presents with rapidly
developing, painful skin ulcers hallmarked by undermined borders and peripheral erythema …

Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …

Lung cancer is the most common and fatal malignant tumor in the world. The tumor
microenvironment (TME) is closely related to the occurrence and development of lung …

Tumour necrosis factor-α (TNF) is a multifunctional cytokine. First recognized as an
endogenous soluble factor that induces necrosis of solid tumours, TNF became increasingly …

The intestinal epithelium constitutes an indispensable single-layered barrier to protect the
body from invading pathogens, antigens or toxins. At the same time, beneficial nutrients and …

The advent of anti-TNF agents as the first approved targeted therapy in the treatment of
inflammatory bowel disease (IBD) patients has made a major impact on our existing …

Inflammatory bowel diseases (IBD), including colitis ulcerosa and Crohn's disease, are
chronic diseases of the gastrointestinal tract for which the cause has not been fully …

Background NLRP3 inflammasome mediates IL-1β maturation, therefore plays a vital role in
the development of IBD. Curcumin is known for possessing strong anti-inflammatory …

The tumor microenvironment (TME) plays key roles in promoting disease progression in the
aggressive triple-negative subtype of breast cancer (TNBC; Basal/Basal-like). Here, we took …

Arthritis is inflammation of the joints accompanied by osteochondral destruction. It can take
many forms, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. These …