[PDF][PDF] Intestinal epithelial cell autophagy is required to protect against TNF-induced apoptosis during chronic colitis in mice

J Pott, AM Kabat, KJ Maloy - Cell host & microbe, 2018 - cell.com
Genome-wide association studies have linked polymorphisms in the autophagy gene
ATG16L1 with susceptibility to inflammatory bowel disease (IBD). However, the cell-type …

Inflammatory cytokines: from discoveries to therapies in IBD

I Marafini, S Sedda, V Dinallo… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Although the etiology of inflammatory bowel diseases (IBD) remains unknown,
accumulating evidence suggests that the intestinal tissue damage in these disorders is due …

[HTML][HTML] ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious …

JW Baddley, F Cantini, D Goletti… - Clinical Microbiology …, 2018 - Elsevier
Background The present review is part of the ESCMID Study Group for Infections in
Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and …

A new venue of TNF targeting

S Steeland, C Libert, RE Vandenbroucke - International journal of …, 2018 - mdpi.com
The first Food and Drug Administration-(FDA)-approved drugs were small, chemically-
manufactured and highly active molecules with possible off-target effects, followed by …

Cepharanthine ameliorates dextran sulphate sodium‐induced colitis through modulating gut microbiota

HG Wang, MN Zhang, X Wen, L He… - Microbial …, 2022 - Wiley Online Library
Cepharanthine (CEP) is an active alkaloid isolated from Stephania Cepharantha Hayata. It
is reported that the anti‐inflammatory properties of CEP could be employed to treat a variety …

The role of tissue-resident macrophages in the development and treatment of inflammatory bowel disease

S Ma, J Zhang, H Liu, S Li, Q Wang - Frontiers in cell and …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, is a
refractory disease with many immune abnormalities and pathologies in the gastrointestinal …

Polysaccharide from Gracilaria Lemaneiformis prevents colitis in Balb/c mice via enhancing intestinal barrier function and attenuating intestinal inflammation

R Han, L Wang, Z Zhao, L You, S Pedisić… - Food …, 2020 - Elsevier
This study explored the preventive effects of polysaccharide extracted from Gracilaria
Lemaneiformis in mice with colitis induced by dextran sulfate sodium (DSS). FT-IR spectrum …

The future of biosimilars: maximizing benefits across immune-mediated inflammatory diseases

HU Kim, R Alten, L Avedano, A Dignass, F Gomollón… - Drugs, 2020 - Springer
Biologics have transformed the treatment of immune-mediated inflammatory diseases such
as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). Biosimilars—biologic …

Therapeutic effects of genistein in experimentally induced ulcerative colitis in rats via affecting mitochondrial biogenesis

TS Alharbi, ZS Alshammari, ZN Alanzi… - Molecular and Cellular …, 2024 - Springer
Ulcerative colitis (UC) is an inflammatory bowel disease that affects the mucosa of the colon,
resulting in severe inflammation and ulcers. Genistein is a polyphenolic isoflavone present …

[HTML][HTML] Study of tumor necrosis factor receptor in the inflammatory bowel disease

RF Souza, MAF Caetano, HIR Magalhães… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) and Crohn's disease (CD) are part of Inflammatory Bowel Diseases
(IBD) and have pathophysiological processes such as bowel necrosis and enteric neurons …