IBD treatment is undergoing a transformation with an expanding repertoire of drugs targeting
different aspects of the immune response. Three novel classes of drugs have emerged in the …

Arecoline is an alkaloid extracted from betel nut, which has various pharmacological effects.
In the present study, we showed that arecoline aggravated experimental acute ulcerative …

Evidence shows that intestinal inflammation, oxidative stress, and injury of mucosal barrier
are closely related to the pathogenesis of ulcerative colitis (UC). Huang-lian-Jie-du …

Cellular heterogeneity poses an immense therapeutic challenge in cancer due to a constant
change in tumor cell characteristics, endowing cancer cells with the ability to dynamically …

Increasing insights into the immunopathogenesis of inflammatory bowel diseases [IBD] have
led to the advent of targeted therapies that inhibit crucial mediators of the inflammatory …

Introduction: Inflammatory bowel disease (IBD) is a systemic disease with immune
abnormalities that can affect the entire digestive tract. A high percentage of patients with IBD …

There is a growing interest in therapeutically targeting the inflammatory response that
underlies age-related chronic diseases including obesity and type 2 diabetes. Through …

Purpose Immune imbalances in major depressive disorder (MDD) have been targeted by
anti-inflammatory treatment approaches in clinical trials to increase responsiveness to …

Such testing and trying time probably never seen before in the human history. The novel
coronavirus disease abbreviated as COVID-19 is the ongoing health crisis which entered …

Intestinal immunity and homeostasis are maintained through the regulation of cytokine
trafficking, microbiota, necrosis and apoptosis. Intestinal immunity and homeostasis …