Vitamin D is widely known to regulate bone health, but there is increasing evidence that it
may also ameliorate colitis through inflammation, cell proliferation and apoptosis, and the …

FDA-approved anti-TNFα biopharmaceuticals are successful in treating a range of
autoimmune diseases. However, not all anti-TNFα products are identical in their patient …

Purpose ABP 710 has been developed as a biosimilar to infliximab reference product (RP).
The objective of this study was to assess analytical similarity (structural and functional) …

Background and aims Tumour necrosis factor-α (TNF) antagonists have improved the
management of inflammatory bowel disease (IBD), however, their usage and administration …

Humira®(adalimumab) by AbbVie has been the top-selling biologic drug product for the last
few years–reaching nearly $20 billion in annual sales in 2018. Upon the October 2018 …

Lactic acid bacteria (LAB) are among the most widely used microorganisms in food
fermentation. However, some LAB species can also be used as live vehicles for the in situ …

Methods In this 52-week, prospective, multicenter, single-cohort, noninterventional,
observational, postmarketing surveillance study, patients with moderate to severe UC …

This study aimed to develop a pH-responsive folic acid-grafted organic/inorganic hybrid
nanocomposite system for site-selective oral delivery of therapeutic antibodies. A folic acid …

Introduction: Medical treatment of pediatric inflammatory bowel diseases (IBD) has been
greatly changed by the introduction of a number of biologic agents that are able to target …

Pyoderma gangrenosum (PG) is a rare, immune-mediated skin disease classified into the
group of neutrophilic dermatoses. Although a number of studies confirmed the central role of …