Ischemic colitis is resulted from an inadequate blood supply to a segment or entire colon.
Polydeoxyribonucleotide (PDRN), extracted from salmon sperm, has been reported to exert …

Members of the Notch family and chronic inflammation were each separately demonstrated
to have prominent malignancy-supporting roles in breast cancer. Recent investigations …

Inflammatory bowel disease (IBD) is a chronic disease that requires lifelong medication and
whose incidence is increasing over the world. There is currently no cure for IBD, and the …

Background Immune thrombocytopenia (ITP) is a common autoimmune disease
characterized by loss of immune tolerance to platelet autoantigens leading to excessive …

Simple Summary Hormone receptor-positive (HR+)/HER2− breast cancer is driven by
extracellular cues within the tumor microenvironment (TME) including hormonal …

Intestinal epithelial cells form a tight barrier to act as selective physical barriers, repelling
hostile substances. Tumor necrosis factor-α (TNF-α) is a well characterized pro-inflammatory …

Simple Summary Immune checkpoint blockades (ICBs) to PD-L1 have led to major
breakthroughs in cancer therapy, but in triple-negative breast cancer (TNBC) success rates …

Introduction Inflammatory bowel disease (IBD) is a complex disease, caused by aberrant
immune responses to environmental stimuli where genetic, metabolomic, and environmental …

Mucosal healing comprises a key goal of ulcerative colitis (UC) treatment. Anterior gradient
protein 2 (AGR2) plays an important role in maintaining intestinal homeostasis in UC …

Background: Ulcerative colitis is one of the main entities of inflammatory bowel diseases.
The clinical course of this immune-mediated disorder is marked by unpredictable …