Mitochondrial function and gastrointestinal diseases

PS Haque, N Kapur, TA Barrett, AL Theiss - Nature Reviews …, 2024 - nature.com
Mitochondria are dynamic organelles that function in cellular energy metabolism,
intracellular and extracellular signalling, cellular fate and stress responses. Mitochondria of …

[HTML][HTML] Potential impact of diet on treatment effect from anti-TNF drugs in inflammatory bowel disease

V Andersen, AK Hansen, BL Heitmann - Nutrients, 2017 - mdpi.com
We wanted to investigate the current knowledge on the impact of diet on anti-TNF response
in inflammatory bowel diseases (IBD), to identify dietary factors that warrant further …

[HTML][HTML] Qingfeiyin decoction inhibits H1N1 virus infection via modulation of gut microbiota and inflammatory pathways in a murine model

X Li, M Wang, C Liu, Y Xiao, M Li, C Ban… - Frontiers in …, 2022 - frontiersin.org
Influenza virus-caused lung infection and its pandemic outbreaks are a persistent public
health challenge. The H1N1 subtype is the most common type of influenza infection …

[HTML][HTML] Adalimumab decorated nanoparticles enhance antibody stability and therapeutic outcome in epithelial colitis targeting

M Ries, B Moulari, MA Shetab Boushehri, ME Ali… - Pharmaceutics, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract with increasing incidence worldwide. Although a deeper understanding of the …

[PDF][PDF] 重症急性胰腺炎肠道屏障障碍及治疗研究进展

崔勇鹤, 王文俊 - 临床急诊杂志, 2019 - lcjz.whuhzzs.com
Severeacutepancreatitis (SAP) oftencausesdamagetointestinalepithelialcells,
destroysintestinal epithelialcellstructure, increasesintestinalmucosalpermeability …

[HTML][HTML] TNFα counteracts interleukin-10 anti-inflammatory pathway through the NOX2-Lyn-SHP-1 axis in human monocytes

M Ben-Khemis, D Liu, C Pintard, Z Song… - Redox Biology, 2023 - Elsevier
TNFα-mediated signaling pathways play a pivotal role in the pathogenesis of inflammatory
diseases such as rheumatoid arthritis (RA) and inflammatory bowel disease (IBD) by …

[HTML][HTML] The first WHO international standard for adalimumab: dual role in bioactivity and therapeutic drug monitoring

M Wadhwa, C Bird, E Atkinson, I Cludts… - Frontiers in …, 2021 - frontiersin.org
The expanded availability of adalimumab products continues to widen patient access and
reduce costs with substantial benefit to healthcare systems. However, the long-term success …

[HTML][HTML] Dual biological therapy and small molecules in pediatric inflammatory bowel disease

F Penagini, L Lonoce, L Abbattista, V Silvera… - Pharmacological …, 2023 - Elsevier
Inflammatory bowel diseases (IBDs) including Crohn's disease (CD), ulcerative colitis (UC)
and inflammatory bowel disease unclassified (IBD-U) are chronic inflammatory disorders …

[HTML][HTML] Monocytes from infliximab-resistant patients with Crohn's disease exhibit a disordered cytokine profile

F Gaiani, BM Rotoli, F Ferrari, A Barilli, R Visigalli… - Scientific Reports, 2020 - nature.com
Crohn's disease (CD) is a chronic inflammatory disorder characterized by immune response
dysregulation. Tumor necrosis factor-α (TNFα) is a key cytokine in the pathogenesis of CD …

[HTML][HTML] Selective forms of therapy in the treatment of inflammatory bowel diseases

A Kofla-Dłubacz, K Akutko, E Krzesiek, T Jamer… - Journal of Clinical …, 2022 - mdpi.com
Selective interference with the functioning of the immune system consisting of the selective
blockade of pro-inflammatory factors is a modern, promising, and developing strategy for the …